Intracellular iron regulation, infections and the effect of LPS endotoxins

pattismith

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I've been trending a little high - but within range - for blood iron, and low for ferritin. My most recent labs, however, had me out-of-range high for blood iron, and right on the border for out-of-range low ferritin. High iron, low ferritin; both trending in opposite directions.

So, unless I had a one-off lab error, or have iron poisoning ( I kinda doubt it as I take no iron suppliments), I'm at a loss.
Low ferritine can be also associated with hypothyroidism.

Maybe some other iron related tests could be usefull
 
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pattismith

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A 2017 study on hematochromatosis showed that a high CD4/CD8 ratio is an aggravating factor:

"Our data indicate that homozygosity for the HLA-A*03 allele significantly increases the risk of excessive iron loading in Norwegian p.C282Y homozygous male patients.

In addition, low CD8 + cell number or high CD4 + cell number further increases the risk of excessive iron loading. "