Insitol hexanicotinate interfere with methylation?

[Adlyfrost]

This is also called no-flush niacin. Would like to take a supplement with 75mgs per serving but not sure.

 

[traray]

I like your question and was hoping someone would answer.....I take this occasionally combined with choline and have wondered if it was a good idea.

 

[Little Bluestem]

Would that be inositol hexanicotinate? I take a supplement that just says 'inositil'. It is a form of niacin that is also sometime called B9. Mine are 750 mg capsules, so it may not be the same thing.

 

[adreno]

This is also called no-flush niacin. Would like to take a supplement with 75mgs per serving but not sure.

I don't believe such a small dose of B3 would interfere. However, you might want to take your methyl supps in the morning, and the B3 in the evening.

 

[adreno]

Would that be inositol hexanicotinate? I take a supplement that just says 'inositil'. It is a form of niacin that is also sometime called B9. Mine are 750 mg capsules, so it may not be the same thing.

I believe you're thinking of Inositol Hexaphosphate (IP-6), this is not a form of B3.

 

[whodathunkit]

@Adlyfrost: In my experience any little bit of *any form* of supplemental niacin can interfere with methylation, at least when I was starting out. I tried all forms, including inositol hexanicotinate. Even really, really small amounts of niacin would cause me problems. Even a small amount of of the so-called "active" form NADH, which supposedly is symptom-free because it requires no processing in the body for the body to use it.

I have to do my B vitamins piecemeal to avoid niacin completely. I'm thinking about trying some again, however, since I'm much more stable than I used to be. We'll see.

Worth noting is that I do drink milk and eat unrefined whole grain, so it could be that I am getting enough niacin from my food and didn't need any supplemental.

But you asked was it possible and yes, IME it is possible. Plus, 75mg seems like a big dose