Overstressed
Senior Member
- Messages
- 406
- Location
- Belgium
Hi Redo,
I just googled, and this is one of the links I had found: http://www.hiv-reservoir.net/index....s-Eradication/il-7-an-hiv-disappointment.html
It's a recent report, though, I still question if Pellegrini's research is the same, or just based on IL-7. It seems to me, Pellegrini got a step further with the IL-7 research and discovered the SOCS-3 gene behaviour with respect to IL-7. On the other hand, the current trials are just administering IL-7, where Pellegrini clearly talks about switching SOCS-3 on/off for little time periods, in order to get the T-cells grouped together to fight the virus off. He does this because otherwise there will be a HUGE immune reaction, when you abruptly switch off SOCS-3, and this might be causing more damage to our system than the virus does.
So, to me, Pellegrini brought the IL-7 research a (huge) step further, in my humble opinion.
Concerning the cancer, I must say that I heard this here on the national radio, where HIV-specialists had spoken about the current and future therapies. They said, although HAART keeps the virus good under control, it doesn't do that with the cancer. More, they exactly can predict WHEN HIV-infected people would get cancer, and that was infection date + 35 years.
I don't know whether this is applicable to all infected ones, because genetics play also a role, I think. However, I'm not a doctor, I just try to give the information as it was said.
Take good care,
OS.
I just googled, and this is one of the links I had found: http://www.hiv-reservoir.net/index....s-Eradication/il-7-an-hiv-disappointment.html
It's a recent report, though, I still question if Pellegrini's research is the same, or just based on IL-7. It seems to me, Pellegrini got a step further with the IL-7 research and discovered the SOCS-3 gene behaviour with respect to IL-7. On the other hand, the current trials are just administering IL-7, where Pellegrini clearly talks about switching SOCS-3 on/off for little time periods, in order to get the T-cells grouped together to fight the virus off. He does this because otherwise there will be a HUGE immune reaction, when you abruptly switch off SOCS-3, and this might be causing more damage to our system than the virus does.
So, to me, Pellegrini brought the IL-7 research a (huge) step further, in my humble opinion.
Concerning the cancer, I must say that I heard this here on the national radio, where HIV-specialists had spoken about the current and future therapies. They said, although HAART keeps the virus good under control, it doesn't do that with the cancer. More, they exactly can predict WHEN HIV-infected people would get cancer, and that was infection date + 35 years.
I don't know whether this is applicable to all infected ones, because genetics play also a role, I think. However, I'm not a doctor, I just try to give the information as it was said.
Take good care,
OS.
