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IDO Metabolic Trap Hypothesis Published Today

To follow up a bit, Dr. Davis did mention in his speech at the Albert Einstein College of Medicine that the IDO1 inhibiting cancer drugs caused extreme fatigue. There were a few drugs that were developed to inhibit IDO1. The one I am assuming he’s talking about is Indoximod, due to it having the highest percentage of subjects with fatigue as a side effect (58.6%,“Biology of T Cells - Part A“). @HTester or anyone for that matter, feel free to correct me if I’m missing the mark on this.