@Abrin No it wouldn’t. My theory is that it was spread through sexual contact. Also that CFS is heterogeneous. I believe that the type I have has been spread through repeated exchange of bodily fluids via sexual contact. Maybe the amount of pathogen has been building up in her as we have more of these exchanges over time until it reached a point it started causing symptoms. What you have, from context clues, seems to be something in your family genetics.