The crux of this lecture was about Cheneys ideas on Oxygen Toxicity and then on his current treatment plan. The talk presented a great deal of technical research information, with displays of IVRT and ECHO graphs and studies, which Cheney has applied to his patients.
Dr. Cheney initiated the talk by stating his concept of CFS as a compensatory mechanism to contain the redox problem (at the heart of it), and that fatigue is a mechanism for keeping worse things from happening. This theme reappears throughout the talk.
The talk was filled with familiar information about diastolic dysfunction. He feels that almost all CFS patients have diastolic dysfunction. 100 % of CFS patents have an energy related cardiac problem. One of the primary symptoms of diastolic dysfunction is Orthostatic Intolerance (a problem with standing). He feels that CFS is a severe oxidative stress disorder, resulting from some provocation, or insult viral or bacterial. He thinks that antiviral therapy is only effective in the beginning of the disease. He spent some time talking about the four phases of the disease.
CFS patients cannot get oxygen into their tissues. If you administer oxygen to the patient, they get worse. Cheney believes that oxygen is kept out as a compensation for keeping something worse from happening and the system accepts the consequences as compensation for not getting something worse. With his testing method, Cheney detects a 21% loss in energy in 30 seconds when oxygen is administered to patients. He says that the CFS condition is close to a fetal physiology in two ways - 40% have PFO (an opening in the heart), and all have oxygen toxicity.
Treatment of oxygen toxicity is in control of the outcome of this disease. Treat the oxygen toxicity correctly and the oxygen toxicity goes away and the patient gets better.
CFS patients have a defect in oxygen handling systems. This includes damage to red blood cells. The body compensates by keeping oxygen out and the result is low energy. Cheney discussed the four adaptations to low oxygen - and most CFS patients have all four. One of them is the methylation block another important defense mechanism against oxygen toxicity. The push crash phenomenon is basically is a failure of the HPA axis to control oxygen toxicity.
NAPDH is low, anabolically blocked which results in P450 becoming uncoupled, leading to all sorts of problems.
Treatment
Dr. Cheney feels that the best treatment follows the best understanding of leverage. He calls this the control point, and he believes in CFS this control point is oxygen toxicity. He describes himself as having gone beyond just treating the symptoms, or searching for the etiology or for specific viral culprits. He is interested in finding and attacking the control point, and getting patients back to a more functional state. Everything that he knows points to CFS as an oxygen toxic state. He asks himself: what is it that makes the oxygen toxicity go away?
SO; what can we do?
don't pulsed magnetic fields help with this?
any thoughts; i can;t afford to see Cheney.
Paul
Dr. Cheney initiated the talk by stating his concept of CFS as a compensatory mechanism to contain the redox problem (at the heart of it), and that fatigue is a mechanism for keeping worse things from happening. This theme reappears throughout the talk.
The talk was filled with familiar information about diastolic dysfunction. He feels that almost all CFS patients have diastolic dysfunction. 100 % of CFS patents have an energy related cardiac problem. One of the primary symptoms of diastolic dysfunction is Orthostatic Intolerance (a problem with standing). He feels that CFS is a severe oxidative stress disorder, resulting from some provocation, or insult viral or bacterial. He thinks that antiviral therapy is only effective in the beginning of the disease. He spent some time talking about the four phases of the disease.
CFS patients cannot get oxygen into their tissues. If you administer oxygen to the patient, they get worse. Cheney believes that oxygen is kept out as a compensation for keeping something worse from happening and the system accepts the consequences as compensation for not getting something worse. With his testing method, Cheney detects a 21% loss in energy in 30 seconds when oxygen is administered to patients. He says that the CFS condition is close to a fetal physiology in two ways - 40% have PFO (an opening in the heart), and all have oxygen toxicity.
Treatment of oxygen toxicity is in control of the outcome of this disease. Treat the oxygen toxicity correctly and the oxygen toxicity goes away and the patient gets better.
CFS patients have a defect in oxygen handling systems. This includes damage to red blood cells. The body compensates by keeping oxygen out and the result is low energy. Cheney discussed the four adaptations to low oxygen - and most CFS patients have all four. One of them is the methylation block another important defense mechanism against oxygen toxicity. The push crash phenomenon is basically is a failure of the HPA axis to control oxygen toxicity.
NAPDH is low, anabolically blocked which results in P450 becoming uncoupled, leading to all sorts of problems.
Treatment
Dr. Cheney feels that the best treatment follows the best understanding of leverage. He calls this the control point, and he believes in CFS this control point is oxygen toxicity. He describes himself as having gone beyond just treating the symptoms, or searching for the etiology or for specific viral culprits. He is interested in finding and attacking the control point, and getting patients back to a more functional state. Everything that he knows points to CFS as an oxygen toxic state. He asks himself: what is it that makes the oxygen toxicity go away?
SO; what can we do?
don't pulsed magnetic fields help with this?
any thoughts; i can;t afford to see Cheney.
Paul