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ScienceDaily posted this article about fluoride consumption where scientists come to the conclusion that some children develop mild fluorosis because they consume too much fluoride. But instead of saying that we maybe should be careful with the intake of too much fluoride especially for infants they claim:
http://www.sciencedaily.com/releases/2010/10/101025161156.htm
"fluoride has been proven to prevent tooth decay, and mild (enamel) fluorosis does not negatively affect dental health or quality of life."
Of course fluoride does not negatively affect dental health, that is why we put it into tooth paste. I want to know if fluoride can have other negative effects not related to teeth!
But it gets even more ridiculous. During the whole text they refer to "mild enamel fluorosis" which appears as barely noticeable faint white lines or streaks on tooth enamel that may occur when children ingest excess fluoride while their teeth are developing. Don't get me wrong but it's just awesome that they tell the reader that these faint white lines don't affect the quality of life, who would have guessed that.
"Nearly all of the fluorosis in our study participants was mild. A recent review of the effects of mild dental fluorosis on oral health-related quality of life concluded that the effect of mild fluorosis was not adverse and could even be favorable," according to the study."
To kind of advice or encourage people to consume high enough amounts of fluoride which lead to mild fluorosis and not cut back on the intake is just stupid in my eyes.
Recent Pubmed abstracts about the possible dangers of Fluoride:
2010 Oct 23. Molecular mechanisms of fluoride toxicity.
...However, in the last decade, interest in its undesirable effects has resurfaced due to the awareness that this element interacts with cellular systems even at low doses. In recent years, several investigations demonstrated that fluoride can induce oxidative stress and modulate intracellular redox homeostasis, lipid peroxidation and protein carbonyl content, as well as alter gene expression and cause apoptosis. Genes modulated by fluoride include those related to the stress response, metabolic enzymes, the cell cycle, cell-cell communications and signal transduction...
PMID: 20650267
_____________________________________________________________
2010 Oct 23. Fluoride-Induced Oxidative Stress in Three-Dimensional Culture of OS732 Cells and Rats.
...Despite its recognized importance as an endemic disease, little is known about how fluoride directly impacts on osteoblasts. We previously reported that fluoride-stimulating monolayer-cultured osteoblast proliferation or inhibiting cell viability depended on fluoride-exposure concentration and period, both accompanied with active oxidative stress...
PMID: 20972717
________________
...However, other elements present in drinking water, such as fluoride, copper, zinc, or iron could also have an effect on cognitive impairment or modify any Aluminium neurotoxicity...
PMID: 20378957
_____________________
...We have shown that chronic fluorosis patients had left ventricular diastolic and global dysfunctions.
PMID: 20206377
_________
...As evident in this study the antioxidative nature of selenium coupled with its reversal effect on metabolic enzymes in brain of mice treated with fluoride suggests its use as antidote agent against fluorosis.
PMID: 20143719
http://www.sciencedaily.com/releases/2010/10/101025161156.htm
"fluoride has been proven to prevent tooth decay, and mild (enamel) fluorosis does not negatively affect dental health or quality of life."
Of course fluoride does not negatively affect dental health, that is why we put it into tooth paste. I want to know if fluoride can have other negative effects not related to teeth!
But it gets even more ridiculous. During the whole text they refer to "mild enamel fluorosis" which appears as barely noticeable faint white lines or streaks on tooth enamel that may occur when children ingest excess fluoride while their teeth are developing. Don't get me wrong but it's just awesome that they tell the reader that these faint white lines don't affect the quality of life, who would have guessed that.
"Nearly all of the fluorosis in our study participants was mild. A recent review of the effects of mild dental fluorosis on oral health-related quality of life concluded that the effect of mild fluorosis was not adverse and could even be favorable," according to the study."
To kind of advice or encourage people to consume high enough amounts of fluoride which lead to mild fluorosis and not cut back on the intake is just stupid in my eyes.
Recent Pubmed abstracts about the possible dangers of Fluoride:
2010 Oct 23. Molecular mechanisms of fluoride toxicity.
...However, in the last decade, interest in its undesirable effects has resurfaced due to the awareness that this element interacts with cellular systems even at low doses. In recent years, several investigations demonstrated that fluoride can induce oxidative stress and modulate intracellular redox homeostasis, lipid peroxidation and protein carbonyl content, as well as alter gene expression and cause apoptosis. Genes modulated by fluoride include those related to the stress response, metabolic enzymes, the cell cycle, cell-cell communications and signal transduction...
PMID: 20650267
_____________________________________________________________
2010 Oct 23. Fluoride-Induced Oxidative Stress in Three-Dimensional Culture of OS732 Cells and Rats.
...Despite its recognized importance as an endemic disease, little is known about how fluoride directly impacts on osteoblasts. We previously reported that fluoride-stimulating monolayer-cultured osteoblast proliferation or inhibiting cell viability depended on fluoride-exposure concentration and period, both accompanied with active oxidative stress...
PMID: 20972717
________________
...However, other elements present in drinking water, such as fluoride, copper, zinc, or iron could also have an effect on cognitive impairment or modify any Aluminium neurotoxicity...
PMID: 20378957
_____________________
...We have shown that chronic fluorosis patients had left ventricular diastolic and global dysfunctions.
PMID: 20206377
_________
...As evident in this study the antioxidative nature of selenium coupled with its reversal effect on metabolic enzymes in brain of mice treated with fluoride suggests its use as antidote agent against fluorosis.
PMID: 20143719