Contaminated Cell Line 'RustyJ'
- Mackay, Aust
I wont know without doing some investigating. I suspect this might include biological drugs, that is things like antibodies, but there are lots of drugs that have been discussed over the years for this kind of thing. There are a wide range of cytokines involved, and this means we have many targets. With many targets comes many drugs, and potential drugs, and drugs overllooked by pharma because they didn't see a need for them.
If this study is replicated then you might see Pharma finally getting involved, but only for new or newer drugs. Repurposing old drugs will have to be researched with other funding.
Let me say again that this will probably require a drug combination, which may be why it has been so hard to find by chance. Also, the initial targets may be critical factors found in the cytokine network.
Whether this treatment will have any impact on long term patients is less certain. If immune exhaustion is the key then it might. If activated microglia is the key, then other treatments may be necessary, either on their own or in combination with the anti-cytokine treatments.
Suppressing cytokines may not work. Note, suppressed cytokine in later-stage patients and symptoms persist.
There is also the concern that there is a reason the cytokines are elevated, and by suppressing them, that agent may itself become more potent.
Another point to consider, I still have no colds or common infections after 25 years, so I am still in the early stage? I don't have any test results to support this, but it seems my cytokine profile may not have changed.
Do other later-stage patients still suffer from so-called cytokine storms (if that is what the 24hr attacks are)?