Hello everyone
This is my first post on this site!
I recently found that I have the MTHFR a1298c Heterozygous mutation.
I believe this to be the cause of all of my symptoms which are basically, demotivation, anhedonia, poor focus/concentration, and just feeling generally un-enthused with life.
I can't seem to find much CLEAR info about what supplements I should be taking for this particular mutation (1298). Should I be taking L-MTHF or Folinic Acid (Calcium Folinate) and how much?
Same goes for B12, do I need MethylB12? HydroxyB12? AdenB12?
What other supplements should I consider? (If only I could get me some BH4 in Australia)
I have had brief periods of success where I feel absolutely epic (full of life, enthused, energetic, able to focus and happy) with 1000mcg HydroxyB12 (first thing in morning), 400mcg L-MTHF 3x day (every 6hrs) and 300mg N-A-Tyrosine 2x day (with the first two MTHFs)... However I can never get the feelings to last, I feel good for a day or two at most, then gradually the benefits I was feeling start to get less and less (over about a week) until I feel the supps are no longer doing anything at all :/
Have currently stopped taking anything for a week so that I can start back up again, but unsure what I will do differently to try maintain the good feeling?
Am I on the right track at all???? What could I do differently?
Any help would be greatly appreciated
Many Thanks
Daniel
This is my first post on this site!
I recently found that I have the MTHFR a1298c Heterozygous mutation.
I believe this to be the cause of all of my symptoms which are basically, demotivation, anhedonia, poor focus/concentration, and just feeling generally un-enthused with life.
I can't seem to find much CLEAR info about what supplements I should be taking for this particular mutation (1298). Should I be taking L-MTHF or Folinic Acid (Calcium Folinate) and how much?
Same goes for B12, do I need MethylB12? HydroxyB12? AdenB12?
What other supplements should I consider? (If only I could get me some BH4 in Australia)
I have had brief periods of success where I feel absolutely epic (full of life, enthused, energetic, able to focus and happy) with 1000mcg HydroxyB12 (first thing in morning), 400mcg L-MTHF 3x day (every 6hrs) and 300mg N-A-Tyrosine 2x day (with the first two MTHFs)... However I can never get the feelings to last, I feel good for a day or two at most, then gradually the benefits I was feeling start to get less and less (over about a week) until I feel the supps are no longer doing anything at all :/
Have currently stopped taking anything for a week so that I can start back up again, but unsure what I will do differently to try maintain the good feeling?
Am I on the right track at all???? What could I do differently?
Any help would be greatly appreciated
Many Thanks
Daniel