Hi everybody:
I suffer from severe gastroparesis. I can only take 3 foods (fruit, turkey and bread), and in very small amounts. I have lost more than 10 kg, and I’m loosing weight every day.
I think I have gastroparesis, although I haven’t been tested for it. However, some prokinetics such as alizapride or metoclopramide (dopamine antagonists) have been really useful in the past, but I developed tolerance to these drugs. I have also tried Motilium and Spasmomen, with no benefits. In this regard, neither HCL nor digestive enzymes are helpful either.
My G.I. symptoms include, mostly, very severe dyspepsia 4-5 hours after eating something that I don't tolerate. I'm really desperate as I'm afraid of getting malnourished.
I'm trying Mestinon, as I have read some folks describing that it helps for grastroparesis (plus this property has been shown in a couple of studies). I took only 1 dose of 15 mg for a few days, but it gave me strong GI symptoms, including bloating, cramps and gut pain/inflammation.
For those who have taken mestinon, do these GI symptoms improve over time? Would you recommend to give it a try until I can tolerate a higher dose? I really don't know what to do, because I cannot afford many days eating even less due to these symptoms.
Also, can you recommend any other drug that acts as a prokinetic? I remember that 15 years ago, just after falling sick, I also had severe GI symptoms, and they went away by taking an antidepressant (problem is that I don't remember which one I took).
Thank you so much in advance for your help. Please let me make clear that all drugs I try, I do it under my doctor's supervision (thing is that he is more lost than me...).
Best wishes!
Sergio
I suffer from severe gastroparesis. I can only take 3 foods (fruit, turkey and bread), and in very small amounts. I have lost more than 10 kg, and I’m loosing weight every day.
I think I have gastroparesis, although I haven’t been tested for it. However, some prokinetics such as alizapride or metoclopramide (dopamine antagonists) have been really useful in the past, but I developed tolerance to these drugs. I have also tried Motilium and Spasmomen, with no benefits. In this regard, neither HCL nor digestive enzymes are helpful either.
My G.I. symptoms include, mostly, very severe dyspepsia 4-5 hours after eating something that I don't tolerate. I'm really desperate as I'm afraid of getting malnourished.
I'm trying Mestinon, as I have read some folks describing that it helps for grastroparesis (plus this property has been shown in a couple of studies). I took only 1 dose of 15 mg for a few days, but it gave me strong GI symptoms, including bloating, cramps and gut pain/inflammation.
For those who have taken mestinon, do these GI symptoms improve over time? Would you recommend to give it a try until I can tolerate a higher dose? I really don't know what to do, because I cannot afford many days eating even less due to these symptoms.
Also, can you recommend any other drug that acts as a prokinetic? I remember that 15 years ago, just after falling sick, I also had severe GI symptoms, and they went away by taking an antidepressant (problem is that I don't remember which one I took).
Thank you so much in advance for your help. Please let me make clear that all drugs I try, I do it under my doctor's supervision (thing is that he is more lost than me...).
Best wishes!
Sergio