Hello,
my name is Santino, I am 27 years old and I live in Germany.
I was by many doctors in Germany and had many diagnoses:
- moderate depression
- general anxiety disorder
- panic disorder
My definitive diagnoses are:
- alopecia areata (over my whole body I lost nearly all hair)
- Vitiligo
- chronic proctitis (which I seem to have under control when I avoid certain food)
- my kidneys where aslso attacked by my immune system.
My last psychiatric diagnosis was bipolar disorder II ultra rapid cycling. This matches with my symptoms a lot, but I know that I have a big influence on the symptoms with using or avoiding foods or using or avoiding supplements. So I cannot see myself in the paradigma of psychiatric medicine.
I don´t have panic attack or general anxiety anymore. Also I don´t have severe depression anymore.
I got there by using psychotherapy but at most by learning which foods I don´t tolerate. Especially anxiety just comes with specific food choices. My depressive mood swings where there all the time until I switched to a ketogenic diet. This diet in combination with low histamine diet lead to a loss of extreme states of depression.
Since then I don´t have the extremes anymore.
But what I always have (and since a year now it is inhibiting me in my everyday life) is brain fog, long subdepressive states, loss of energy (concentration, focus), many sensivities to medications or foods (get cold symptoms from some things). I also often feel "mixed states": a state between depressive/anxious/irritated".
I want to get rid of this fucking brain fog. I cannot get my work done and everything seems meaningless if I cannot do anything.
I hope that I can get help here.
After trying many things and contacting many doctors I found the thing about the MTHFR gene and general SNP-testing.
I decided to do these tests and you can see my results in the file I attached!
I tried a Multivitamin with metafolin and methylcobalamin in it (also the other b vitamins where in it), but I noticed my anxiety coming up at this day altough the dose was very small ( e.g. 133mg metafolin, 170 methycobalamin)
I hadn´t these symptoms long time and my life is quite standard at this moment so I can rule out which factors lead to symptoms. I will try it again but it seems that adressing my SNPs lead to anxiety.
My actual diet is:
Macronutrients:
Protein: between 50g and 90g per day
Fat: between 100-300g per day
Carbohydrate: less than 30g per day
Food I eat at this moment:
fresh meat and fish from all sources (low in histamine)
Vegetables: Zucchini and carrots most, sometimes Brokoli or green beans
Fat from pork, goose, ghee, meat/fish, krill oil, Flax seed oil, olive oil
My questions are:
1. Do you have advice for me? What should I try next?
2. Ae here people who experienced relief of brain fog and fatigue by using the genetic testing thing?
Kind regards!
Santino
My SNP:
VDR Bsm rs1544410 TT +/+
BHMT-02 rs567754 TT +/+
BHMT-04 not found n/a n/a
BHMT-08 rs651852 TT +/+
AHCY-01 rs819147 CT +/-
AHCY-02 not found n/a n/a
AHCY-19 rs819171 CT +/-
CBS C699T rs234706 AG +/-
CBS A360A rs1801181 GG -/-
CBS N212N not found n/a n/a
SHMT1 C1420T not found n/a n/a
COMT V158M rs4680 GG -/-
COMT H62H rs4633 CC -/-
COMT P199P rs769224 GG -/-
VDR Bsm rs1544410 TT +/+
VDR Taq rs731236 GG -/-
MAO A R297R rs6323 G -/-
ACAT1-02 rs3741049 GG -/-
MTHFR C677T rs1801133 AG +/-
MTHFR 03 P39P rs2066470 AG +/-
MTHFR A1298C rs1801131 GT +/-
MTR A2756G rs1805087 AA -/-
MTRR A66G rs1801394 AG +/-
MTRR H595Y not found n/a n/a
MTRR K350A rs162036 AA -/-
MTRR R415T not found n/a n/a
MTRR A664A rs1802059 GG -/-
I can provide more SNPs if necessary. I tested at 23andme!
my name is Santino, I am 27 years old and I live in Germany.
I was by many doctors in Germany and had many diagnoses:
- moderate depression
- general anxiety disorder
- panic disorder
My definitive diagnoses are:
- alopecia areata (over my whole body I lost nearly all hair)
- Vitiligo
- chronic proctitis (which I seem to have under control when I avoid certain food)
- my kidneys where aslso attacked by my immune system.
My last psychiatric diagnosis was bipolar disorder II ultra rapid cycling. This matches with my symptoms a lot, but I know that I have a big influence on the symptoms with using or avoiding foods or using or avoiding supplements. So I cannot see myself in the paradigma of psychiatric medicine.
I don´t have panic attack or general anxiety anymore. Also I don´t have severe depression anymore.
I got there by using psychotherapy but at most by learning which foods I don´t tolerate. Especially anxiety just comes with specific food choices. My depressive mood swings where there all the time until I switched to a ketogenic diet. This diet in combination with low histamine diet lead to a loss of extreme states of depression.
Since then I don´t have the extremes anymore.
But what I always have (and since a year now it is inhibiting me in my everyday life) is brain fog, long subdepressive states, loss of energy (concentration, focus), many sensivities to medications or foods (get cold symptoms from some things). I also often feel "mixed states": a state between depressive/anxious/irritated".
I want to get rid of this fucking brain fog. I cannot get my work done and everything seems meaningless if I cannot do anything.
I hope that I can get help here.
After trying many things and contacting many doctors I found the thing about the MTHFR gene and general SNP-testing.
I decided to do these tests and you can see my results in the file I attached!
I tried a Multivitamin with metafolin and methylcobalamin in it (also the other b vitamins where in it), but I noticed my anxiety coming up at this day altough the dose was very small ( e.g. 133mg metafolin, 170 methycobalamin)
I hadn´t these symptoms long time and my life is quite standard at this moment so I can rule out which factors lead to symptoms. I will try it again but it seems that adressing my SNPs lead to anxiety.
My actual diet is:
Macronutrients:
Protein: between 50g and 90g per day
Fat: between 100-300g per day
Carbohydrate: less than 30g per day
Food I eat at this moment:
fresh meat and fish from all sources (low in histamine)
Vegetables: Zucchini and carrots most, sometimes Brokoli or green beans
Fat from pork, goose, ghee, meat/fish, krill oil, Flax seed oil, olive oil
My questions are:
1. Do you have advice for me? What should I try next?
2. Ae here people who experienced relief of brain fog and fatigue by using the genetic testing thing?
Kind regards!
Santino
My SNP:
VDR Bsm rs1544410 TT +/+
BHMT-02 rs567754 TT +/+
BHMT-04 not found n/a n/a
BHMT-08 rs651852 TT +/+
AHCY-01 rs819147 CT +/-
AHCY-02 not found n/a n/a
AHCY-19 rs819171 CT +/-
CBS C699T rs234706 AG +/-
CBS A360A rs1801181 GG -/-
CBS N212N not found n/a n/a
SHMT1 C1420T not found n/a n/a
COMT V158M rs4680 GG -/-
COMT H62H rs4633 CC -/-
COMT P199P rs769224 GG -/-
VDR Bsm rs1544410 TT +/+
VDR Taq rs731236 GG -/-
MAO A R297R rs6323 G -/-
ACAT1-02 rs3741049 GG -/-
MTHFR C677T rs1801133 AG +/-
MTHFR 03 P39P rs2066470 AG +/-
MTHFR A1298C rs1801131 GT +/-
MTR A2756G rs1805087 AA -/-
MTRR A66G rs1801394 AG +/-
MTRR H595Y not found n/a n/a
MTRR K350A rs162036 AA -/-
MTRR R415T not found n/a n/a
MTRR A664A rs1802059 GG -/-
I can provide more SNPs if necessary. I tested at 23andme!
Attachments
Last edited: