No, just for a few days. I took the increased gas as a sign of “not good” and quit.
I think probiotics and other gut microbiome experiments have to be run longer, because transient changes are likely.
I wonder if xifaxan is effective on reducing these bacteriophages?
Nope. Antibiotics work against becteria, while bacteriophages are viruses, so they'd be unaffected, aside from having fewer hosts to multiply in.
I thought of an example of how ecosystems are not simple. Some people might picture the digestive tract as stainless steel tubing, that can be flushed, sterilized, and replanted with the desired microbes. By the same assumption, invasive weeds should take over all land. I live in the woods, with a grassy driveway and some trails through the forest. My driveway has lots of tall buttercup (invasive weed), but it never spreads further than a couple of feet from the driveway. It outcompetes native vegetation on packed soil, but fails on regular forest soil. I find a few patches on old logging roads and cutlines, but they don't spread. Plantain has a similar pattern, but survives really hard-packed soil better. Dandelions do well in mowed areas (and tilled garden soil
), but not elsewhere. Thistles do well in more places, but don't survive in forest shade. Ox-eye daisies do well on dry soil along the gravel road (calcium chloride may be involved) but don't spread from there. Likewise, native species have some fairly narrow niches.
The human digestive tract may be like my forest. You can apply large amounts of bacterial strains from one end or the other, but that doesn't guaranteed that they'll find a spot where they'll survive. Some might reach a good spot for them, but they'll be out-competed by some other strain. Maybe they'll be vulnerable to bacteriophages that some other strain is hosting. Maybe a strain that does really well in someone else's gut won't survive in yours because your genetics produce a slightly different mucus layer or produce different amounts of some chemical.
So, don't think that changing your gut microbiome is as simple as flushing and replanting. It's far more complicated. I think many of the success stories are from people who simply got lucky, and we don't hear the stories of all the other people who tried the same thing and didn't get lucky. It is possible to make improvements, but think of it as a low-chance-to-win lottery that requires buying lots of tickets, rather than a straightforward 'follow these simple steps to success' method.
I'll point out that I did play the game (antibiotics, probiotics, diet change, etc) without success, and then apparently got lucky with accidental food poisoning, which seems to have cured the type IV food sensitivity I'd had. I didn't know that my microbiome was involved, and I think it's unlikely I'd have had success intentionally changing my microbiome. Thank you spoiled coconut milk!