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Gc-Maf 2-nd generation from Japan

lobba123

Senior Member
Messages
250
i contacted them and they had a patient with hbv+hcv+Non-Hodgkin's lymphoma, he cleared everything except hcv (hcv is curable almost 100% with new antivirals on trials so not an issue)

this is the Cost:

GcMAF is 8300yen/0.5ml vial.

8 vials 0.5ml -- 66,400yen*
16 vials 0.5ml -- 132,800yen*
24 vials 0.5ml -- 199,200yen*

* Plus shipping and handling by express mail.

is 8000yen about 75euros?

i wish a researcher will assay their gcmaf.....the only problem may be quick delivery from japan

Hi,

I was wondering if this was posted already before:

http://www.saisei-mirai.or.jp/gan/macrophage_eng.html

It's a clinic in Japan and apparently they produce -what they call- a 2nd generation Gc-Maf, which is more potent than the first generation. It looks to me this site has a lot of information on Gc-Maf.


Best regards,
OS.
 

Daffodil

Senior Member
Messages
5,873
so about $100 for 0.5ml...not bad.

this gcmaf thing is getting huge ...wonder when the drug companies/fda will try to ruin it for us.
 

Sushi

Moderation Resource Albuquerque
Messages
19,934
Location
Albuquerque
i contacted them and they had a patient with hbv+hcv+Non-Hodgkin's lymphoma, he cleared everything except hcv (hcv is curable almost 100% with new antivirals on trials so not an issue)

this is the Cost:

GcMAF is 8300yen/0.5ml vial.

8 vials 0.5ml -- 66,400yen*
16 vials 0.5ml -- 132,800yen*
24 vials 0.5ml -- 199,200yen*

* Plus shipping and handling by express mail.

is 8000yen about 75euros?

i wish a researcher will assay their gcmaf.....the only problem may be quick delivery from japan

I believe one potential problem with this for ME/CFS is that there is a huge range of the number of nannograms you might get in your order and many of us taking GcMAF have found that we need to have a low and reliably consistant dose. I believe it is very concentrated too. There is another thread on this that gives more details.

The explanation for the variance in dosage from vial to vial is that each vial (or batch of vials?) comes from an individual donor. These are things to consider before jumping to order. Also, the number of mls means little unless you know how many nannograms there are per ml.

Best,
Sushi
 

L'engle

moogle
Messages
3,173
Location
Canada
How much does a treatment like this tend to work out to, for the quantity that ME patients might need?
 

lobba123

Senior Member
Messages
250
i do agree that without an indipendent assay it could be simple water, and also useless for CFS, i think it is valuable (if real gcmaf) for cancer and viral infections like hiv-hbv
also delivery to europe may be a big issue

this is their answer on vials content
The GcMAF we produce is 10-20 times more concentrated than other GcMAF that is available, and we always use 0.5ml once or twice weekly, not 0.25ml. Each 0.5 ml vial contains approximately 1500-2500 ng GcMAF.

I believe one potential problem with this for ME/CFS is that there is a huge range of the number of nannograms you might get in your order and many of us taking GcMAF have found that we need to have a low and reliably consistant dose. I believe it is very concentrated too. There is another thread on this that gives more details.

The explanation for the variance in dosage from vial to vial is that each vial (or batch of vials?) comes from an individual donor. These are things to consider before jumping to order. Also, the number of mls means little unless you know how many nannograms there are per ml.

Best,
Sushi
 

lobba123

Senior Member
Messages
250
it is multiple use and it is so extremely cheap, but we need assays on potency since it may be simple water until assayed

shipment japan to europe may be an issue, i think 2-3 days delivery time not less

Shame. If it was able to be multiple use that would be extremely cheap!
 

hixxy

Senior Member
Messages
1,229
Location
Australia
I'm located in Australia, so Japan is better for me. I know some clinics in New Zealand are using GcMAF from Japan. Has the European GcMAF been assayed by a 3rd party? If GcMAF was initially developed in Japan, you would hope they'd be reliable creating it.
 

lobba123

Senior Member
Messages
250
yes assayed by many researchers

it doesn t matter if it was disocvered in japan, it needs to be assayed to prove it is not water

I'm located in Australia, so Japan is better for me. I know some clinics in New Zealand are using GcMAF from Japan. Has the European GcMAF been assayed by a 3rd party? If GcMAF was initially developed in Japan, you would hope they'd be reliable creating it.
 

camden7

[banned as spam]
Messages
9
If GcMAF was initially developed in Japan, you would hope they'd be reliable creating it.

The new GcMAF was developed by researchers who continued Dr Yamamoto's work in Japan. They have been working on GcMAF for nearly 2 decades. In that respect, yes it is probably the highest quality GcMAF available anywhere.
 
Messages
1
Is there anyone about who has actually used the Japanese GcMAF? Or is planning to?

Well, I've been trying to find reports from people with cancer using Gc-MAF, but not many are reporting in cancer forums. This seems to be the most active forum about Gc-MAF users, so I'll give my two cents here. I decided to go with the Saisei clinic Gc-MAF, as it is supposed to be more potent than others available, which I believe is important due to the fact that, besides macrophage activation (which can apparently be achieved with very low doses), the Gc-MAF protein has been shown to have antitumor properties even without its effect on the immune system. So injecting with larger doses may be more beneficial in cancer treatment, and the contact at the clinic has stated that they have had more success treating cancer patients with the higher dosage. I don't think think this is water - it has a definite yellowish color that may be indicative of the amount of Gc-MAF. Purchasing from the clinic was straightforward - I wired the money on a Wednesday, it was shipped on Friday, and I received the product the following Monday. My first injection was a full dose, and the only side effect I experienced was extreme fatigue for about a day and a half, as if my immune system were fighting off something - hopefully the cancer. I have only taken four doses so far, so I won't know if it's working for another two weeks. Each dose is contained in its own vial, so I froze all but the first dose. It should be easy to get a number of reduced doses from each vial, but remember some is always left behind in the syringe. I hope this helps.
 

garcia

Aristocrat Extraordinaire
Messages
976
Location
UK
It's a clinic in Japan and apparently they produce -what they call- a 2nd generation Gc-Maf, which is more potent than the first generation.

For most of us with ME the issue with Gc-MAF hasn't been lack of potency, but rather the opposite, i.e. being able to tolerate the potency. I for one would not want to take a more potent product as the original is potent enough. The issue is how to control the potency (i.e. inflammatory side effects).
 

Sushi

Moderation Resource Albuquerque
Messages
19,934
Location
Albuquerque
For most of us with ME the issue with Gc-MAF hasn't been lack of potency, but rather the opposite, i.e. being able to tolerate the potency. I for one would not want to take a more potent product as the original is potent enough. The issue is how to control the potency (i.e. inflammatory side effects).

I second that! Especially as this company gives such a huge range in the possible number of nannograms per vial. It could be Russian roulette! (speaking for ME patients, not cancer or HIV)

Sushi
 

camden7

[banned as spam]
Messages
9
Since this GcMAF doesn't usually have any significant side effects, and is very different from regular GcMAF, the only way to know whether ME patients react in the same way would be to try it, with an experienced doctor. You might start with 0.1 ml dose and go from there. GcMAF, even at high doses is nothing compared with the side effects of chemotherapy. Even with ME patients, the side effect might only be fatigue. Chemotherapy leaves many people sick for days and days, and sometimes requires hospitalisation. If the dose of chemo is much lower, there are less or no side effects and it might make the patient feel better, but it won't be effective as a therapy. So it's a balance between side effects and treatment outcome.
 

Sushi

Moderation Resource Albuquerque
Messages
19,934
Location
Albuquerque
camden7;254232... said:
GcMAF, even at high doses is nothing compared with the side effects of chemotherapy. Even with ME patients, the side effect might only be fatigue. Chemotherapy leaves many people sick for days and days, and sometimes requires hospitalisation. If the dose of chemo is much lower, there are less or no side effects and it might make the patient feel better, but it won't be effective as a therapy. So it's a balance between side effects and treatment outcome.

Sorry, gotta disagree here! Of course I (and probably no ME/CFS patients) have taken the Japanese version, but a GcMAF dose of as little as 100 ng can give ME patients extremely serious side effects--I know from experience as do quite a few others here. Of course it isn't the GcMAF directly, it is the activation of the huge number of macrophages. A number of us are taking only 10 ng and getting good results with symptoms and lab results.

This cannot be compared to chemotherapy because we are not dealing with cancer. GcMAF and chemotherapy work very differently. Also, ME/CFS patients respond very differently to cancer patients. The doses that work for cancer are too high for ME/CFS patients. And "more" GcMAF (more potent) is usually worse for ME/CFS patients. Most specialists are starting patients on about 25 nannograms.

So I am actually worried about the huge variation in nannograms from vial to vial from the Japanese company. An ME/CFS patient could order this and inject it with potentially very serious side effects. Does the Japanese company require a doctor's prescription and continuous monitoring? Because certain labs are necessary to follow the progress (or assess danger) for ME/CFS patients taking GcMAF.

Please don't compare this to the use of GcMAF for HIV or cancer. We are dealing with a very different beast!

Sushi
 

Dan_USAAZ

Senior Member
Messages
174
Location
Phoenix, AZ
[WIKI][/WIKI]
The new GcMAF was developed by researchers who continued Dr Yamamoto's work in Japan. They have been working on GcMAF for nearly 2 decades. In that respect, yes it is probably the highest quality GcMAF available anywhere.

Hi camden7,
Could you please share references or supporting material that lead you to make this post? Saisei Mirai has what appears to be a very professional website and have mastered social media, but I have failed to find any meaningful information about them. Part of the problem may be my inability to read kanji.

Also, I find it interesting (odd) that their website appears to be 100% kanji, except for the GcMAF page marketing GcMAF. Maybe they expect to market most of their services in Japan and only GcMAF to the rest of the world?

Any information that you could provide in support of the statements you have made would be greatly appreciated.

Thank you,
Dan
 

hixxy

Senior Member
Messages
1,229
Location
Australia
Hello Dan,
I am working for Saisei Mirai and I will be glad to give you information about what we are dealing with.
Not only in Japan, our activity also covers wherever in the world.

If you're still interested in, please email us 2ndGcMAF@gmail.com

Waiting for your reply!
MAC


You may be able to instill far better confidence in the general public and the people on this forum if you were able to use an email at a saisei mirai company domain for your communications?

Say for instance: 2ndGcMAF@saisei-mirai.or.jp

I don't know if this is possible or feasible. Just a thought.

hixxy
 

lobba123

Senior Member
Messages
250
saisei gcmaf is sourced from tokushima university from the group who first discovered and made gcmaf and keep making research on it.i guess they wont miss cancer patients in japan in future decades due to fukishima radioacitvity

http://www.saisei-mirai.or.jp/menekinaika/index.html
Therapy is to activate the immune system to maximize inherent in human nature.
Research and development collaboration with the University of Tokushima Graduate School.