I’m also curious for an update, and have more to contribute.
Panic attacks and throat constriction, without anxiety, reminds me of high histamine. I had a panic attack once, likely from low serotonin, and it did not have throat constriction. So to me that sounds like an allergy
I once found this article claiming that SALT is a natural antihistamine:
https://www.watercures.org/natural-antihistamine.html
I personally have experienced severe shortness of breath and rapid breathing that seemed to be hyponatremia / low sodium. This appears to be a chronic issue for me, and today I’m getting a bottle of 1g salt tablets from Amazon to do some experimenting. I also have chronic high heart rate, which also often spikes after eating, and suspect/hope it’s related to sodium because I’ve tried so many other things with little effect.
I also have low cortisol. Adrenal cortex extract turned out to be the BEST supplement in my arsenal, and I’ve been a mad scientist who has self-tested about 200 supplements. Cardiovascular Research has a 350mg capsule that I went for after working my way up a with 50mg capsule and realizing the more I took, the more it worked. It worked so well I started over-producing cortisol at one point in the evening. Furthermore, it’s the ONE supplement that has helped me fall back asleep after 3am awakenings (waking up after 3-4h of sleep).
I’m currently modulating my cortisol curve with ashwaghanda and skullcap for general stress support, and holy basil for when cortisol is high. Cortex seems best to take in morning, and/or maybe with lunch, and/or when waking up in the middle of the night. Taking it with dinner + having a stressful evening sent me into high cortisol where I was super energized, but couldn’t get to sleep for hours. That said, sometimes when I notice low cortisol symptoms in the evening, cortex seems to help; but I’m testing 50-150mg in evening now, not 350mg.
I have also endured low dopamine and low serotonin. Both seem to be extraordinarily improved with cortex, through dopamine a bit less than serotonin. The safest dopamine supplements in order are: DLPA, tyrosine, mucuna (however the most potent begins with mucuna and works backwards through those three). Cortex + mucuna at 3am has been a winning combo. Even when I sleep bad, dopamine supplements make me feel 80-90% normal.
I don’t remember what HVA etc is off the top of my head, but if it indicates low dopamine production that can point to gene mutations and/or cofactor deficiencies, which could point you in new directions. Iron is needed I think? And BH4.
BH4 relates to nitric oxide and the urea cycle. I personally had low ornithine so had to study this. The urea cycle (ornithine, citrulline, arginine) deals mainly with ammonia. High ammonia symptoms can be extremely debilitating! I’m prone to high ammonia because of the CBS gene mutation. Which also made me have sulfur sensitivity, whose symptoms are even more debilitating! Molybdenum was the solution for sulfur symptoms. Yucca and ceylon cinnamon (not normal store cinnamon) can help with high ammonia. Though I don’t think I’ve figured out my situation yet as I’m actually awake after drinking soda, which has the ingredient “caramel coloring,” which is a morbid synthetic flavoring made from ammonia and sulfur! Anyway, getting your urea cycle in order will be important for ammonia (and preventing debilitating symptoms), BH4 (assisting neurotransmitters), and nitric oxide. There’s a lot going on with this one cluster.
As always, I recommend the Nutrigenomics page on heartfixer.com. Even if you don’t know your genes, you can search certain terms like “nitric oxide” to understand how the body’s processing things, and look up pathway images such as the urea cycle to see how everything flows. The urea cycle in particular runs through ornithine, arginine, and citrulline in a loop cycle, so if something is deficient or blocked up there, I think that’s a pretty important area to focus.
And of course, urea leads to urination. There could be something related there. However, I have made some distinct correlations with my own ruination and sense of bladder fullness. A very full feeling, even urgent or “burning-ish” indicates high potassium. I know, because at one point I was testing 1-5g. (Yes, a lot of 100mg tablets.! Whereas when my bladder is clearly full but feels fine like I can hold it without burning/sensitivity, that’s adequate sodium.
From my perspective, sodium is a common denominator.
This article asserts that normal blood sodium levels do not correlate to body stores/needs.
https://drinklmnt.com/blogs/health/normal-sodium-levels
As for “normal levels,” this doctor suggests sodium must be above 141 or it’s deficient.
