sometexan84
Senior Member
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I found out why Eiger Biopharmaceuticals, creator of Pegylated Interferon Lambda, will not return any of my messages. They do NOT want to lose their Orphan Drug status.
There's great potential for this drug in treating Enterovirus B infections in ME/CFS.
And it's not just me who thinks this...
Maureen Hanson (of the recent The Enterovirus Theory of Disease Etiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Critical Review), appears to be in favor of a Peginterferon trial for ME/CFS, as she was helping me locate relevant contacts for such a trial.
Jane Zhou (of the recent Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus) said "enteroviruses are very sensitive to IFN lamda. it will definitely be an excellent drug for treating enterovirus infections" when I asked about Peginterferon Lambda.
However, since this drug has "orphan" status, Eiger gets many many benefits and perks. And if they were to use it to treat ME/CFS, they'd lose this orphan status.
Orphan drugs treat rare diseases that have less than 200,000 in the U.S. They use PEG-IFN-lambda to treat Hep D virus, which has only 100,000 in U.S.
With Orphan status, they get the following....
There's great potential for this drug in treating Enterovirus B infections in ME/CFS.
And it's not just me who thinks this...
Maureen Hanson (of the recent The Enterovirus Theory of Disease Etiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Critical Review), appears to be in favor of a Peginterferon trial for ME/CFS, as she was helping me locate relevant contacts for such a trial.
Jane Zhou (of the recent Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus) said "enteroviruses are very sensitive to IFN lamda. it will definitely be an excellent drug for treating enterovirus infections" when I asked about Peginterferon Lambda.
However, since this drug has "orphan" status, Eiger gets many many benefits and perks. And if they were to use it to treat ME/CFS, they'd lose this orphan status.
Orphan drugs treat rare diseases that have less than 200,000 in the U.S. They use PEG-IFN-lambda to treat Hep D virus, which has only 100,000 in U.S.
With Orphan status, they get the following....
- tax incentives
- exclusivity (special patent and marketing rights protections)
- government subsidies for clinical research
- can jack up the price for massive profit (orphan drug companies don’t have to disclose their pricing strategies)
- regulatory shortcuts (less FDA regulatory requirements and oversight)