Cort
Phoenix Rising Founder
- Messages
- 7,383
It just shows how complicated it all is doesn't it? RNase L was (is?) a big thing.
Several studies suggested that RNase L fragmentation was commonly found in ME/CFS and, importantly, they were able to correlate symptom severity with the degree of fragmentation: it seemed to be a key part of this disease. (Some later studies have not been so successful, however.)
But here we find - at least according to this group - that RNase L is not correlated with XMRV diagnosis. How could this be?; how is it that a common finding in Dr. Peterson's set of patients (RNase L) - does not correlate with another common finding in his set of patients (XMRV)? There are apparently a significant # of patients with RNase L problems without XMRV and vice versa.
Then there are cytokines? the Science paper said as I remember that the patients in the study had high IL-8 levels. Dr. Klimas just did a study showing ME/CFS patients had LOW Il-8 levels. It's just very complex!
I'm ready for anything....
Several studies suggested that RNase L fragmentation was commonly found in ME/CFS and, importantly, they were able to correlate symptom severity with the degree of fragmentation: it seemed to be a key part of this disease. (Some later studies have not been so successful, however.)
But here we find - at least according to this group - that RNase L is not correlated with XMRV diagnosis. How could this be?; how is it that a common finding in Dr. Peterson's set of patients (RNase L) - does not correlate with another common finding in his set of patients (XMRV)? There are apparently a significant # of patients with RNase L problems without XMRV and vice versa.
Then there are cytokines? the Science paper said as I remember that the patients in the study had high IL-8 levels. Dr. Klimas just did a study showing ME/CFS patients had LOW Il-8 levels. It's just very complex!
I'm ready for anything....