Thanks, that's good information. I think this is about more than nutrition - it's about broken signals. Fixing gut dysbiosis has never done anything for me. I was candida free for 10 years and as soon as I included a tiny bit of sugar in my diet everything came back. I have taken massive amounts of probiotics for 20+ years and I started forgetting to take them last week after i took the high potency sulphur.
The H2S and thiosulfate act as signals in the blood. When I dissolve the elemental sulfur under my tongue it goes into my blood and probably makes hydrogen sulfide and thiosulfate - but only a tiny bit. It makes enough to act as a signal but that's it.
Many experts compare chronic fatigue to chronic sepsis and having experienced it, i agree. Thiosulfate apparently helped some septic rats and it may be helping me too.
I'd like to see if sodium thiosulfate is a possible treatment for CFS. If there's anybody you can talk to, please do.
overview of H2S and sepsis research in here:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562801/
I'm not taking any supplements - just multivitamins, vitamin c, b complex, and probiotics. So there's no confusion about what's improving my health right now.