Dr David Tuller: Bruce Levine on 'How Not To Conduct a Randomised Clinical Trial'

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http://www.virology.ws/2018/09/18/t...w-not-to-conduct-a-randomized-clinical-trial/

Trial By Error: Bruce Levin on “How Not to Conduct a Randomized Clinical Trial”
18 SEPTEMBER 2018
By David Tuller, DrPH

When I first began examining the PACE trial in detail, I turned to clinical trial experts to vet my concerns. One of them was biostatistician Bruce Levin, a professor at Columbia University’s Mailman School of Public Health, to whom I was referred by a mutual colleague. After he reviewed the trial, he pronounced it to be a mess—a conclusion that fueled my determination to investigate the matter.
Professor Levin identified many faults in the PACE trial’s design.
 
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