Does anyone find it a bit odd, his advice on infectivity?
I don't really think there is sufficient evidence on transmission and infectivity. Based on the monkey study, they observed that it does go quickly to tissues and glands. Therefore, it stands to reason that infectivity from sexual activity could last well beyond six weeks.
Also, if it could only be found in the blood of patients within six weeks of infectivity then:
* is it pure coincidence that those tested, but have been sick for years, happened to somehow become infected with this new retrovirus in a 6 week window of testing... what would the odds be on that I wonder?
If so, it would also make it a pure coincidence that MLV found by Lo Alter et al from blood samples that were 15 yrs old, identified in only 8 individuals ( if my memory serves me) must have all got exposed 15 yrs ago within a six week window. That's pretty amazing odds in such a small group, isn't it?
However if I recall, when they redrew fresh blood from these 8 subjects they also tested positive. That would suggest that the virus is not only in the blood for 6 weeks wouldnt it? It is also consistent with what is known of other retroviruses like HIV, that go to tissues and develop latent reseviours, that are capable of viremia dumps and therefore subsequent circulation in the blood.
In view of that, I would say that risk of infectivity remains but is increased, at times of notable symptom increase or crashes.
i am no scientist, but i thought that when they do a real study, like the ones you talk about above, they use a process that makes hard to find viruses easier to see. so even if the viral load is very small, they can still find the virus.
and i think bell was saying that the viral load is high for the first 6 weeks, and thus easy to infect another person. after those 6 weeks, the virus hides in other places in the body, but not the blood. so viral load in the blood is low. thus it is harder to transmit.
but if the virus hides in the cervix and cervical fluid (as the money study found), it seems that sexual transmission would be easy. (however, it is hard for a woman's cervical fluid to give a man HIV -- and maybe xmrv? -- unless there is an open cut on his penis, i think, allowing the virus to get into his blood. correct me if i'm wrong.)