I understand that this is just one project for Nath and not his lifelong goal, however when he says he isn't going to become an ME/CFS expert i wonder what he means.
I've watched the video now, and I was expecting the very worst after reading this thread beforehand, so I braced myself for a rough ride, and I was pleasantly surprised. I'm not saying it's perfect but there was some good stuff in the video; He emphasised immunology and autoimmunity, and loads of other really essential stuff.
With regards to not being an expert in ME, I think he meant that he doesn't need to be an expert in ME, but he needs to be an expert in the scientific method, designing trials, and interpreting data: he's interested in the data, and will follow it. That's what he's interested in. He's looking at cells and biological signatures, not the day-to-day difficulties of living with ME. As long as he's got his cohort in place, then he doesn't need to know much about ME. I think he was also being candid; in that he doesn't intend to devote his life to ME, but he's going to do the best he can with this project, so let him get on with it. That was my interpretation anyway.