Dopamine concern

[Gondwanaland]

.I tried B2, and had a terrible reaction. I did not have FMN at that time. And I was titrating from a 100mg capsule, so that likely contributed to the poisoning.

You don't have T4 in your body, right?

 

[ahmo]

You don't have T4 in your body, right?

Probably not. Or if so, at very low levels.

 

[Gondwanaland]

Probably not. Or if so, at very low levels.

I suspect this might be the culprit for your bad reaction to riboflavin .

 

[Gondwanaland]

http://ajcn.nutrition.org/content/47/3/481.full.pdf

In the hypothyroid rat the flavin adenine dinucleotide (FAD) content of the liver is similar to that observed in rats maintained on a riboflavin-deficient diet. Thyroxine regulates the enzyme flavin kinase.

Human adults with hypothyroidism have levels of erythrocyte glutathione reductase (EGR), an FAD-containing enzyme, in the range indicative of riboflavin deficiency, which can be corrected with thyroxine therapy.

 

[ahmo]

I suspect this might be the culprit for your bad reaction to riboflavin .

And my + reaction to FMN?

 

[Gondwanaland]

And my + reaction to FMN?

It skips the conversion by T4 giving you the end product of the T4+B2 reaction.

 

[TheChosenOne]

Homozygous:

• COMT V158M
• COMT H62H
• VDR Bsm

Heterozygous:

• COMT P199P
• MTRR A66G
• MTRR A664A
• BHMT-02
• BHMT-08
• CBS C699T
• CBS A360A

I have similar SNPs and have similar problems. I'm considering myself as having bipolar (only in case of stress or lack of sleep).

@ppodhajski
Because I don't want to hijack this thread, I've made a new thread here.