Does anyone USE CREATINE?

[keenly]

I used to use KRE ALKALYN which does not convert to creatinine with GREAT benefits and visible ones too. It helped me to maintain a good muscle mass instead of being skinny.

I stopped because dr yasko mentioned something to do with viruses and its compenents(amino acids that that contribute to viruses).

I then tried it again last year but felt extremely thirsty and agitated.

Now i know with a partial methylation block with don't have the same creatine synthesis, right? Meaning there are no stores in muscle= fatigue?

I was thinking of trying again and drinking etc

anyone know much about this? I can;t find ANY Dr opinions; wonder if CHENEY has one? He should test this!!!!!!!!!!!

Paul

 

[L'engle]

My boyfriend (he has CFS/exercise intolerance) takes creatine sometimes. He finds it does help with muscle fatigue, but sometimes he gets a pain around the kidney area from it or swollen toes that are darker colored. So I'd be careful with it if you notice any strange effects!

 

[FunkOdyssey]

Creatine raises DHT levels which may accelerate XMRV replication so I steer clear of it.

Clin J Sport Med. 2009 Sep;19(5):399-404.
Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players.

van der Merwe J, Brooks NE, Myburgh KH.
Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.

Abstract

OBJECTIVE: This study investigated resting concentrations of selected androgens after 3 weeks of creatine supplementation in male rugby players. It was hypothesized that the ratio of dihydrotestosterone (DHT, a biologically more active androgen) to testosterone (T) would change with creatine supplementation.

DESIGN: Double-blind placebo-controlled crossover study with a 6-week washout period.

SETTING: Rugby Institute in South Africa.

PARTICIPANTS: College-aged rugby players (n = 20) volunteered for the study, which took place during the competitive season.

INTERVENTIONS: Subjects loaded with creatine (25 g/day creatine with 25 g/day glucose) or placebo (50 g/day glucose) for 7 days followed by 14 days of maintenance (5 g/day creatine with 25 g/day glucose or 30 g/day glucose placebo).

MAIN OUTCOME MEASURES: Serum T and DHT were measured and ratio calculated at baseline and after 7 days and 21 days of creatine supplementation (or placebo). Body composition measurements were taken at each time point.

RESULTS: After 7 days of creatine loading, or a further 14 days of creatine maintenance dose, serum T levels did not change. However, levels of DHT increased by 56% after 7 days of creatine loading and remained 40% above baseline after 14 days maintenance (P < 0.001). The ratio of DHT:T also increased by 36% after 7 days creatine supplementation and remained elevated by 22% after the maintenance dose (P < 0.01).

CONCLUSIONS: Creatine supplementation may, in part, act through an increased rate of conversion of T to DHT. Further investigation is warranted as a result of the high frequency of individuals using creatine supplementation and the long-term safety of alterations in circulating androgen composition. STATEMENT OF CLINICAL RELEVANCE: Although creatine is a widely used ergogenic aid, the mechanisms of action are incompletely understood, particularly in relation to dihydrotestosterone, and therefore the long-term clinical safety cannot be guaranteed.

PMID: 19741313