Consistent with either classic allergy problems or mcas. It means you should test to rule out regular ige allergies and if those come back negative or even if a few come back positive (bc u can have mcas and allergies ), you should test for more mcas tests: tryptase, histamine, prostaglandins, and more (you can look for full list of mcas tests somewhere on this site probably or an mcas site. ). High IgE, especially if it appears more than once and isnt fluke, is definitely meaningful.
Diseases that cause the elevation of serum IgE levels include atopic diseases (asthma, allergic rhinitis, atopic dermatitis, urticaria), parasitic diseases, cutaneous diseases, neoplastic diseases, and immune deficiencies...
MCAS is a condition in which the patient experiences repeated episodes of the symptoms of anaphylaxis – allergic symptoms such as hives, swelling, low blood pressure, difficulty breathing and severe diarrhea. High levels of mast cell mediators are released during those episodes.