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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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If that is anything to do with having ME/CFS, and happening so regularly, it probably would be best to see if as far as work goes if you could may be take a couple of days off each week towards the end of the 2 week period to try to avoid this being triggered off eg work only a week and a half out of every 2.
If this is ME/CFS it could end up getting to the point where that symptom may end up staying with you rather then leaving which would be probably completely disasterous for your work life that happens. My ME/CFS wasnt full time at first and was triggered off regulary with certain things with making a full recovery in between the rounds of it. I really regret not slowing down at that point as maybe it would never have become an ongoing thing.
I got those symptoms by year 5+, Also now I only gets them as a sign of overactive immune system and can be trigger w things like:
Zync over 15mg
Echinacea any amount.
any immune booster med.....
Agreed! Immune 'activators' can cause these symptoms for me.
I got those symptoms by year 5+, Also now I only gets them as a sign of overactive immune system and can be trigger w things like:
Zync over 15mg
Echinacea any amount.
any immune booster med.....
So those things you listed trigger it?
Ditto; there was a thread on this called, I think, "Sick but never sick". There's a significant subset of us who never seem to catch anything at all; or don't react immunologically to what we DO catch.
Within memory subsets, a higher frequency of CD21(+) CD38(-) B cells (>20%) was associated with the presence of ME/CFS
Yes; echinacea and zinc are both reputed to help the immune system fight off pathogens. I sometimes take a blend containing both, if my pathogens are being particularly frisky. However, if I go overboard, I get the symptoms mentioned: very sore lymph nodes (to the point that it hurts to talk), low fever, fatigue worsening, etc.
- CFS/ME patients exhibited alterations in NK receptors and adhesion markers and receptors on CD4(+)T and CD8(+)T cells.
- Moderate CFS/ME patients had:
Severe CFS/ME patients had:
- increased CD8(+) CD45RA effector memory T cells
- SLAM expression on NK cells
- KIR2DL5(+) on CD4(+)T cells
- BTLA4(+) on CD4(+)T central memory cells.
- reduced CD8(+)T central memory LFA-1 total CD8(+)T KLRG1
- naïve CD4(+)T KLRG1
- CD56(dim)CD16(-) NK cell CD2(+) and CD18(+)CD2(+).
- increased CD18(+)CD11c(-) in the CD56(dim)CD16(-) NK cell phenotype
- reduced NKp46 in CD56(bright)CD16(dim) NK cells.
wow that's like an entirely other language to me! Should print it all and take to the docSecond study says:
Whew! That's a lot...
wow that's like an entirely other language to me! Should print it all and take to the doc
Yes those are my flu symptoms triggers, for me is a sign of my immune system to be on overdrive (mostly by something I drank / ate, new supplement.... Sometimes I cannot figure out why.I do immune modulators to stop it and back down on all meds until the immune system clams down.So those things you listed trigger it?
Haven't had PEM in a long time (knock wood) but when I did get it I always got flu-like symptoms with it. Feeling like flu symptoms might be coming on is still (always) a barometer by which I judge my ability to go forward or if I should take a break.
When I think about the pathogens that bother us, they're pathogens that all of the world has, we just can't seem to fight them off like healthies: Candida, Aspergillus, EBV are something that the vast majority of the population has, they just don't have them out of control. It seems as though our ability to recognize new pathogens might be unimpaired, or even boosted, while our ability to 'remember' to fight pathogens we're exposed to seems to be malfunctioning..
I definitely wrote it off too quickly when it first popped up. I think we all come to things when it's our time.I have looked a little at the Resistant Starch challenge thread and never got very far - it didn't seem applicable to me but maybe I wrote it off too quickly.
Sadly, I starting to believe that's kind of like asking how many angels can dance on the head of a pin; it's a question with no concrete answer since the answer is almost entirely subjective. For some the answer to that question could lie with genetics...for others could be prenatal stress...and for still others might be cumulative environmental insults. Probably various combos of the three.The big question is.. what is wrong with our immune systems?