• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.


Does anyone happen to be on the medication digoxin for cardiac isssues, if so have you found it helps your PEM, sensory overload or myalgia at all?

I'ts possible that it may work via HIF1a inhibition thereby reducing lactate production following tissue hypoxia. Of course in the long term this is not ideal, but if it is capable of modifying any of the above outcomes this would be really intriguing. It has to be prescribed and monitored very carefully due to potential for toxicity.