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Derya Unutmaz Jackson Laboratory - announcement Weds 27 Sept

dancer

Senior Member
Messages
298
Location
Midwest, USA
His twitter bio says: Professor at The Jackson Laboratory for Genomic Medicine. Human immunologist, interested in aging research, personalized medicine and technological advances.

And he's tweeted about #millionsmissing and retweeted good articles about me/cfs. Interesting!
 

Seven7

Seven
Messages
3,444
Location
USA
ABOUT DERYA UNUTMAZ, M.D.
Our research primarily focuses on decoding the differentiation, activation and regulation of human T cells for optimal immune responses to infectious diseases and their perturbations during chronic diseases or aging. We have contributed to the understanding of how T cell subsets are disrupted during human diseases, especially during HIV infection. Our lab has made several seminal discoveries about the diversity and mechanisms of immune suppression mediated by regulatory T cells and effect or functions of human Th17 cell subsets.
 

NelliePledge

Senior Member
Messages
807
https://www.jax.org/news-and-insigh...s-federal-grant-for-chronic-fatigue-research#

this announcement of funding from last year was retweeted in response to his tweet

includes this paragraph
Unutmaz proposes to undertake a major study of ME/CFS patients, screening blood samples for potential immunological biomarkers of the disease, and using the results to develop better diagnostic tools and personalized treatments for the disease.
 

HowToEscape?

Senior Member
Messages
626
https://www.jax.org/news-and-insigh...s-federal-grant-for-chronic-fatigue-research#

this announcement of funding from last year was retweeted in response to his tweet

includes this paragraph
Unutmaz proposes to undertake a major study of ME/CFS patients, screening blood samples for potential immunological biomarkers of the disease, and using the results to develop better diagnostic tools and personalized treatments for the disease.


This assumes that the marker is to be found in the blood. To me this sounds like looking under the lamppost: perhaps we have a dysfunction that happens inside of cells, is disseminated in fluids other than the blood, is an interaction between cells and mitochondria, etc.

I don't know enough biology to name all the bodily processes, but I do know that there's a bit more in your body than blood. It just happens that it's very easy to take a bit of blood out and send it to a lab.

Sort of like analyzing the engine oil in the car; you can tell a great deal about what's going on by sending a little used oil out for analysis, but that's not going to find an occluded oil passage which will only become a problem at very low temperatures. Then not enough oil will flow and the engine will seize up, leaving you to freeze to death somewhere in the arctic tundra.
To find the problem you'll either have to chill the whole thing, hook up instruments and carefully measure oil pressure and flow under many different conditions, or disassemble the engine and find the partly blocked passage. Drawing off a little oil and sending it to a lab is rather easy. The engine exam expedition for a hidden defect is not.
 
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