For two weeks (from the end of November to December 17) I took large doses of sublingual, methylated vitamin B12 in drops. The doses were 5000-6000 mcg in divided forms. I haven't been officially diagnosed with a deficiency, but I wanted to help my neuropathic pain, sciatica (etc.) due to fibromyalgia. Doctors have always prescribed me B vitamins, but I wanted to try a little higher doses. Especially since I've heard that you can't overdose on B12 and there are no side effects.
On December 13th I had my first panic attacks in my life. That day I didn't sleep the whole night, not even a minute. My whole body was shaking (especially my hands). I had no reason to be worried, and my body was completely shaken. I didn't know what was happening around me. I felt a strong warmth, hard to describe unreality and depressive states bordering on psychosis. My heart was beating like I had run a marathon. The worst thing was what was happening in my head. That night I felt like all the worst things had taken over me. I had the worst thoughts imaginable, I felt terribly alone, like I was the only person on earth, overwhelming sadness and the belief that it would always be like this - that I would always live in pain (fibromyalgia) and that I would always be alone, unhappy etc.
On December 17th I took another large dose of vitamin B12. It was basically the same thing all over, except I didn't have such negative thoughts. I didn't sleep all night either. The next few days were awful for me. Constant fear and anxiety, severe depression, I cried all the time, everything made me incredibly sad, I didn't know what was happening to me.
I found some info that it could be overmethylation and that niacin should help quickly. At that point I only had niacinamide with me, so on December 25th I started taking 50 mg of niacinamide every hour. I felt a slight improvement, but I still felt absolutely terrible.
In the following days I increased the dose of niacinamide (up to 250 mg 4 times a day) and I started to feel better and better. I still felt depressed, I still had anxiety and I slept 2-3 hours a night, but it was much better than at the beginning. I felt like I was slowly starting to come out of it.
I decided to reduce my niacinamide dose (to 250 mg twice a day) and on January 8th I didn't sleep through the night. On January 9th I only slept for 2 hours. On January 10th I also didn't sleep through the night. I started feeling worse and worse again. After B12 I am very overstimulated and overenergized. I don't feel tired at all and don't feel like sleeping. I took melatonin to try to sleep (it gave me about 4-5 hours of sleep last night, although I woke up every hour), but it made me feel even more depressed. I found information that melatonin is also a methyl donor, so that would explain it.
I wonder how long it will take for this to all be over? Should I take niacin until all symptoms disappear? How long can overmethylation last? Most people write that after 2-4 days of taking niacin all their symptoms disappeared. I took niacinamide for over 2 weeks and I am still a long way from my previous state. It's really, really hard for me.
I've been taking 50mg of niacin every hour for the past two days. It helps a little, but I still feel really, really bad. I'd appreciate any advice.
On December 13th I had my first panic attacks in my life. That day I didn't sleep the whole night, not even a minute. My whole body was shaking (especially my hands). I had no reason to be worried, and my body was completely shaken. I didn't know what was happening around me. I felt a strong warmth, hard to describe unreality and depressive states bordering on psychosis. My heart was beating like I had run a marathon. The worst thing was what was happening in my head. That night I felt like all the worst things had taken over me. I had the worst thoughts imaginable, I felt terribly alone, like I was the only person on earth, overwhelming sadness and the belief that it would always be like this - that I would always live in pain (fibromyalgia) and that I would always be alone, unhappy etc.
On December 17th I took another large dose of vitamin B12. It was basically the same thing all over, except I didn't have such negative thoughts. I didn't sleep all night either. The next few days were awful for me. Constant fear and anxiety, severe depression, I cried all the time, everything made me incredibly sad, I didn't know what was happening to me.
I found some info that it could be overmethylation and that niacin should help quickly. At that point I only had niacinamide with me, so on December 25th I started taking 50 mg of niacinamide every hour. I felt a slight improvement, but I still felt absolutely terrible.
In the following days I increased the dose of niacinamide (up to 250 mg 4 times a day) and I started to feel better and better. I still felt depressed, I still had anxiety and I slept 2-3 hours a night, but it was much better than at the beginning. I felt like I was slowly starting to come out of it.
I decided to reduce my niacinamide dose (to 250 mg twice a day) and on January 8th I didn't sleep through the night. On January 9th I only slept for 2 hours. On January 10th I also didn't sleep through the night. I started feeling worse and worse again. After B12 I am very overstimulated and overenergized. I don't feel tired at all and don't feel like sleeping. I took melatonin to try to sleep (it gave me about 4-5 hours of sleep last night, although I woke up every hour), but it made me feel even more depressed. I found information that melatonin is also a methyl donor, so that would explain it.
I wonder how long it will take for this to all be over? Should I take niacin until all symptoms disappear? How long can overmethylation last? Most people write that after 2-4 days of taking niacin all their symptoms disappeared. I took niacinamide for over 2 weeks and I am still a long way from my previous state. It's really, really hard for me.
I've been taking 50mg of niacin every hour for the past two days. It helps a little, but I still feel really, really bad. I'd appreciate any advice.
