Glynis Steele
Senior Member
- Messages
- 404
- Location
- Newcastle upon Tyne UK
I am a new member, and found these links in relation to CFS, which I think have very important implications. I posted this earlier today, in reply to a member who stated that when he fasted for 3 days, his CFS was hugely improved.
Dla lasts around 3 days, when carbs are stopped. DLA is normally seen by a gastroenterologist, in patients with a shortened bowel. It would be very astounding for them to think of it in a patient with a complete bowel, and I would imagine they would be skeptical, to say the least.
The hospital that tests for d-lactic acidosis is Birmingham Childrens Hospital, UK. They test for adults too. They prefer a gastro to be involved, to interpret the test results, however if the test was positive they would notify the sender by phone to tell them. The test needs to be done in a hospital setting, as the blood needs to be centrifuged within an hour of being taken. The path lab at BCH are very helpful, a really nice bunch.
I get mixed up with micromols and milimoles, the measurements taken, but for example a test of 2.4 would be 2400 with Birmingham Childrens Hospital. Normal dla should be 0-0.25. I enclose some links regarding dla in relation to CFS, and also a link on dla in a short bowel patient, with a good graph of symptoms.
This first one is from another discussion group, where someone with CFS said they had tested postive for dla. The reading of 2.4 would certainly warrant investigation or treatment by a GI, I think they would be astounded to see it though, as they have a very narrow field of vision regarding dla, they almost exclusively see it in short bowel patients. A GP or other dr would not be trained to see that this is a serious condition, or the implications for treatment.
http://www.endfatigue.com/forums/viewtopic.php?f=17&t=1271
This abstract is saying that patients with CFS have bacteria in their stool that are dla producers, and says the symptoms are strikingly similar. I have the full pdf of this, which I have tried to enclose, not sure if it will work as I am a techno-phobe and not good at this sort of thing!
http://www.ncbi.nlm.nih.gov/pubmed/19567398
This is a Newsletter from the Breakspear Hospital (private) regarding CFS and d-lactic acid.
http://www.breakspearmedical.com/files/documents/Issue24Spring2010web_000.pdf
This is the d-lactic in short bowel paper, with a graph of symptoms.
http://hkjpaed.org/details.asp?id=577&show=1234
As I said yesterday, d-lactic lasts up to 80 hours, when you stop eating carbs. It has a circadian rhythm, meaning that it builds up after every meal, peaking in early evening (which I think is why sleep problems are so common in CFS). Maybe cutting carbs out would be a good way of seeing if there are improvements to be had. Also milk sugar counts as a carb, so no milk or soya milk.
Hope this is useful to you, I think it may be the missing link for CFS.
BW
Glynis
Attached Files
2009_Sheedy_In_vi.pdf (252.7 KB, 0 views)
Dla lasts around 3 days, when carbs are stopped. DLA is normally seen by a gastroenterologist, in patients with a shortened bowel. It would be very astounding for them to think of it in a patient with a complete bowel, and I would imagine they would be skeptical, to say the least.
The hospital that tests for d-lactic acidosis is Birmingham Childrens Hospital, UK. They test for adults too. They prefer a gastro to be involved, to interpret the test results, however if the test was positive they would notify the sender by phone to tell them. The test needs to be done in a hospital setting, as the blood needs to be centrifuged within an hour of being taken. The path lab at BCH are very helpful, a really nice bunch.
I get mixed up with micromols and milimoles, the measurements taken, but for example a test of 2.4 would be 2400 with Birmingham Childrens Hospital. Normal dla should be 0-0.25. I enclose some links regarding dla in relation to CFS, and also a link on dla in a short bowel patient, with a good graph of symptoms.
This first one is from another discussion group, where someone with CFS said they had tested postive for dla. The reading of 2.4 would certainly warrant investigation or treatment by a GI, I think they would be astounded to see it though, as they have a very narrow field of vision regarding dla, they almost exclusively see it in short bowel patients. A GP or other dr would not be trained to see that this is a serious condition, or the implications for treatment.
http://www.endfatigue.com/forums/viewtopic.php?f=17&t=1271
This abstract is saying that patients with CFS have bacteria in their stool that are dla producers, and says the symptoms are strikingly similar. I have the full pdf of this, which I have tried to enclose, not sure if it will work as I am a techno-phobe and not good at this sort of thing!
http://www.ncbi.nlm.nih.gov/pubmed/19567398
This is a Newsletter from the Breakspear Hospital (private) regarding CFS and d-lactic acid.
http://www.breakspearmedical.com/files/documents/Issue24Spring2010web_000.pdf
This is the d-lactic in short bowel paper, with a graph of symptoms.
http://hkjpaed.org/details.asp?id=577&show=1234
As I said yesterday, d-lactic lasts up to 80 hours, when you stop eating carbs. It has a circadian rhythm, meaning that it builds up after every meal, peaking in early evening (which I think is why sleep problems are so common in CFS). Maybe cutting carbs out would be a good way of seeing if there are improvements to be had. Also milk sugar counts as a carb, so no milk or soya milk.
Hope this is useful to you, I think it may be the missing link for CFS.
BW
Glynis
Attached Files
2009_Sheedy_In_vi.pdf (252.7 KB, 0 views)