Cytokines study at St Jude's is similar to Dr Mark Davis

[Nickster]

Please see this recent study from St Jude's that is studying T cells

https://www.stjude.org/media-resour...atory-t-cells-may-play-role-in-allergies.html

This is similar to Dr Mark Davis and the immune system. Interesting!

@Janet Dafoe (Rose49) @AshleyHalcyoneH

 

[Murph]

Honestly I'd like someone to really spell out the links between this and Davis, M. They're both interesting and about t cells and that's where my ability to see the connection fades out.

 

[dreampop]

That actually is a really interesting article.

Mice who have a protein (LKB1) knocked out (ty Capecchi) developed exhausted regulatory t-cells which means they stop doing their job particularly well. I think this means the regulatory t-cells lose their ability to downregulate the TH-2 immune system.

Deletion of LKB1 in regulatory T cells disrupted metabolic pathways that support the health and function of the mitochondria. Mitochondria produce energy to power cells. "LKB1 connects immunological signals and cell metabolic programs, especially those related to mitochondrion function," said first author Kai Yang, Ph.D., a staff scientist in Chi's laboratory.

Interesting tidbit linking the mitochondria to immune function. We have so much to learn!

 

[Janet Dafoe]

Please see this recent study from St Jude's that is studying T cells

https://www.stjude.org/media-resour...atory-t-cells-may-play-role-in-allergies.html

This is similar to Dr Mark Davis and the immune system. Interesting!

@Janet Dafoe (Rose49) @AshleyHalcyoneH

I sent this to Ron and Mark. I'll let you know if I hear anything back.