It will depend primarily on the person and their level of severity. For the severe patient, there could be muscle weakness, joint contractures, cardiovascular pathology, peripheral neuropathies, residual pain disorders, balance and proprioception issues, digestion issues, cognitive processing issues and changes in sensation and sensory functions.
For the less severe it may only be one or two of the above.
In my experience the following factors will play a role in the equation:
- Duration of the ME disease presence
- The Severity of the disease
- The presence of remissions or breaks from the disease
- The genetic/physiological predisposition of the person
Disease of long duration, high severity, lack of remission/breaks and a strong genetic predisposition for cardiovascular, digestive, other auto-immune disorders or any other disorder will significantly increase the likelihood that these will be secondary physiological issues that will need to be addressed.