JaimeS
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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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@Hip, that is fascinating!
It shouldn't even require anything that complicated - they should be serologically distinguishable by ELISA. If the MS work is replicated, then tests might be marketed for it - and then it would be a simple matter to look and see if such a thing is present in ME.
If it were just caused by virulent EBV, then one would think that 100% of patients would be helped by ganciclovir and recovery would be nearly complete, but we don't observe anything close to that. Some patients don't even have EBV. So maybe it causes some cases but not others - but again, this causes problems with the issue of similar symptomatology despite different infectious causation, even when comparing viruses that cause completely different syndromes otherwise. This makes me very skeptical.
rs3732378 (CX3CR1 T380M) "AG" or "AA" would be the genotypes for the pathogenic mutation in that one, in case anyone wants to look up their results for it.rs3732378