Emootje
Senior Member
- Messages
- 356
- Location
- The Netherlands
Cholestasis is a pathologic state of reduced bile flow from the liver into the gut.
It is characterized by an accumulation of bile acids in the liver and in the blood.
Hydrophobic bile acids are pro-oxidants causing cell damage.
The similarities between cholestasis findings and ME/CFS findings:

Diagnosis of cholestasis:
Elevations of serum bile acid levels
Therapy cholestasis:
Ursodeoxycholic acid
Soluble fiber
Lecithin
Lipoic acid
Vitamin E
SAM-e
NAC
Could ME/CFS be a mild cholestasis?
Systemic hypotension and renal failure in obstructive jaundice-mechanistic and therapeutic aspects
http://jasn.asnjournals.org/content/5/11/1853.full.pdf
Increased plasma levels of atrial natriuretic peptide and endocrine markers of volume depletion in patients with obstructive jaundice.
http://www.ncbi.nlm.nih.gov/pubmed/9462378
It is characterized by an accumulation of bile acids in the liver and in the blood.
Hydrophobic bile acids are pro-oxidants causing cell damage.
The similarities between cholestasis findings and ME/CFS findings:

Diagnosis of cholestasis:
Elevations of serum bile acid levels
Therapy cholestasis:
Ursodeoxycholic acid
Soluble fiber
Lecithin
Lipoic acid
Vitamin E
SAM-e
NAC
Could ME/CFS be a mild cholestasis?
Systemic hypotension and renal failure in obstructive jaundice-mechanistic and therapeutic aspects
http://jasn.asnjournals.org/content/5/11/1853.full.pdf
Increased plasma levels of atrial natriuretic peptide and endocrine markers of volume depletion in patients with obstructive jaundice.
http://www.ncbi.nlm.nih.gov/pubmed/9462378