Just becasue we have no biomarker does not mean CFS doesn't exist.And I agree with that, to a point. There are scam therapies, there is no doubt about it. But I have found some things that are helpful and do work, even when the official science says they shouldn't. The same science says often that CFS doesn't exist.
So I am more careful not to throw the baby out with the bathwater anymore, and I've seen it happen here sometimes when there is a disagreement about the method used, especially if the method is not strongly backed by science, but again, CFS is also not strongly backed by science. As long as the method isn't harmful, I say it is worth a try or at least to learn what it is, and maybe accept that it helped some people. I think it can be harmful though to discredit a therapy based on our sole perception of which methods can work, and which can't, unless of course there is a clear evidence that the therapy is harmful, like GET.
Science has not disproven the existence of CFS, it simply has not elucidated the mechanism.
Parkinsons disease has no biomarker and often cannot be proven except post mortem. Yet it has a solid diagnostic package that has been built over decades of work by many people and drugs have been found for it. The process of finding those drugs zigzagged, even the simple gold standard drug Levodopa was not easy to discover despite it being the basic standard of care today.
Yet no biomarker or test is available.
Hell Narcolepsy has no biomarker and until the discovery of a new neurochemical in 1998 there was no theories on it either. It also has drug treatments despite no objective test.
Even Alzheimers disease can often only be confirmed with an autopsy.
Thus this is about societal understanding. MS was considered psychosomatic, we know better now becasue a diagnostic test was developed. Parkinsons was also eventually proven to be physical as was Narcolepsy.
The placebo effect is a subject in itself. Hell its been getting stronger in recent decades (for unknown reasons) and often invalidates tests of antidepressants.Agree with positive thinking when cynical or miserable. But positive thinking does not work so good with migraines or back pain afaik. There must be something else. I wonder what.
Is there a chance the guy's nervous system stuck in the fight-or-flee mode causing anxiety translated by his brain into pain&fatigue and later he was able to return to the rest-and-digest mode? I know too little.
And lets not forget denial, the entire CBT/GET "treatment" is designed to use denial to make ME/CFS go away. For psychological conditions it can actually have some tangible effect. Even in physical conditions you can deny things away, even cancer until you die from it. But it never treated the problem.
Finally those who are depressed are often misdiagnosed with ME/CFS. Exercise works for depressed patients. And random pains are also commonplace in depression.
I get that we want to believe in simple cures for our problems but we are doing ourselves a disservice if we fall for them.
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