The CDC can't find CFS much less XMRV.
The CDC studies "chronic unwellness" not CFS. They plan to analyze their findings in 2011. Here are their criteria for the Bibb county registry.
http://www.fatigueregistry.org/sites/fatigueregistry/default.aspx?pid=678#28
• Current severe fatigue persisiting for one month or longer
• One of the following for at least one month:
- Unrefreshing sleep,
- Problems with memory or concentration, or
- Unexplained joint or muscle pain in the lower extremities
• Age: 12 to 59, inclusive
• Body mass index (BMI) les than 40.0
Here is a description of the Canadian Criteria:
http://www.cfids-cab.org/MESA/ccpc.html
The Canadian Expert Consensus Panel has published a medical milestone, the first
clinical case definition for the disease known as myalgic
encephalomyelitis/chronic fatigue syndrome. This definition is clearly a vast
improvement over the CDC's 1994 Fukuda criteria, which led to misunderstanding
in both research and treatment modalities by making "fatigue" a compulsory
symptom but by downplaying or making optional the disease's hallmark of
post-exertional sickness and other cardinal ME/CFS symptoms.
In sharp contrast to the Fukuda criteria, this new clinical case definition
makes it compulsory that in order to be diagnosed with ME/CFS, a patient must
become symptomatically ill after exertion and must also have neurological,
neurocognitive, neuroendocrine, dysautonomic, and immune manifestations. In
short, symptoms other than fatigue must be present for a patient to meet the
criteria. This case definition, which incorporates some of the current research
on dysautonomia, cardiac, and immune problems, was published in the Journal of
Chronic Fatigue Syndrome, Vol. 11 (1) 2003.
It is summarized as follows:
1. POST-EXERTIONAL MALAISE AND FATIGUE: There is a loss of physical and mental
stamina, rapid muscular and cognitive fatigability, post-exertional fatigue,
malaise and/or pain, and a tendency for other symptoms to worsen. A
pathologically slow recovery period (it takes more than 24 hours to recover).
Symptoms exacerbated by stress of any kind. Patient must have a marked degree of
new onset, unexplained, persistent, or recurrent physical and mental fatigue
that substantially reduces activity level.
2. SLEEP DISORDER: Unrefreshing sleep or poor sleep quality; rhythm disturbance.
3. PAIN: Arthralgia and/or myalgia without clinical evidence of inflammatory
responses of joint swelling or redness. Pain can be experienced in the muscles,
joints, or neck and is sometimes migratory in nature. Often, there are
significant headaches of new type, pattern, or severity. [Editor’s note:
neuropathy pain is a common symptom and should be added here as well.]
4. NEUROLOGICAL/COGNITIVE MANIFESTATIONS: Two or more of the following
difficulties should be present: confusion, impairment of concentration and
short-term memory consolidation, difficulty with information processing,
categorizing, and word retrieval, intermittent dyslexia, perceptual/sensory
disturbances, disorientation, and ataxia. There may be overload phenomena:
informational, cognitive, and sensory overload -- e.g., photophobia and
hypersensitivity to noise -- and/or emotional overload which may lead to
relapses and/or anxiety.
5. AT LEAST ONE SYMPTOM OUT OF TWO OF THE FOLLOWING CATEGORIES:
AUTONOMIC MANIFESTATIONS: Orthostatic Intolerance: e.g., neurally mediated
hypotension (NMH), postural orthostatic tachycardia syndrome (POTS), delayed
postural hypotension, vertigo, light-headedness, extreme pallor, intestinal or
bladder disturbances with or without irritable bowel syndrome (IBS) or bladder
dysfunction, palpitations with or without cardiac arrhythmia, vasomotor
instability, and respiratory irregularities.
NEUROENDOCRINE MANIFESTATIONS: loss of thermostatic stability, heat/cold
intolerance, anorexia or abnormal appetite, marked weight change, hypoglycemia,
loss of adaptability and tolerance for stress, worsening of symptoms with stress
and slow recovery, and emotional lability.
IMMUNE MANIFESTATIONS: tender lymph nodes, sore throat, flu-like symptoms,
general malaise, development of new allergies or changes in status of old ones,
and hypersensitivity to medications and/or chemicals.
6. The illness persists for at least 6 months. It usually has an acute onset,
but onset also may be gradual. Preliminary diagnosis may be possible earlier.
The disturbances generally form symptom clusters that are often unique to a
particular patient. The manifestations may fluctuate and change over time.
Symptoms exacerbate with exertion or stress.
This summary is paraphrased from Dr. Kenny van DeMeirleir's book Chronic Fatigue
Syndrome: A Biological Approach, February 2002, CRC Press, pg. 275.
The CDC Bibb county register does rule out:
Bibb County does rule out:
• Pregnancy within past 12 months
• Stroke with no full recovery
• Parkinson’s disease
• Chronic obstructive pulmonary disease (COPD) or congestive heart failure
• Insulin-dependent diabetes
• Uncontrolled diabetes type II (HgbA1c < 9%)
• Anemia
• Uncontrolled hypo- or hyper-thyroidism
• Uncontrolled hypertension (BP > 140/90)
• Sickle cell anemia
• Cancer within 5 years (except basal skin or currentl receiving chemotherapy
• Untreated depression
• Substance abuse problems within the past 2 years
• Anorexia nervosa or bulimia nervosa within the past 5 years
• Schizophrenia, bipolar I or II, or dementia
• Hepatitis B or C
All providers should complete a medical history.
The CDC studies "chronic unwellness" not CFS. They plan to analyze their findings in 2011. Here are their criteria for the Bibb county registry.
http://www.fatigueregistry.org/sites/fatigueregistry/default.aspx?pid=678#28
• Current severe fatigue persisiting for one month or longer
• One of the following for at least one month:
- Unrefreshing sleep,
- Problems with memory or concentration, or
- Unexplained joint or muscle pain in the lower extremities
• Age: 12 to 59, inclusive
• Body mass index (BMI) les than 40.0
Here is a description of the Canadian Criteria:
http://www.cfids-cab.org/MESA/ccpc.html
The Canadian Expert Consensus Panel has published a medical milestone, the first
clinical case definition for the disease known as myalgic
encephalomyelitis/chronic fatigue syndrome. This definition is clearly a vast
improvement over the CDC's 1994 Fukuda criteria, which led to misunderstanding
in both research and treatment modalities by making "fatigue" a compulsory
symptom but by downplaying or making optional the disease's hallmark of
post-exertional sickness and other cardinal ME/CFS symptoms.
In sharp contrast to the Fukuda criteria, this new clinical case definition
makes it compulsory that in order to be diagnosed with ME/CFS, a patient must
become symptomatically ill after exertion and must also have neurological,
neurocognitive, neuroendocrine, dysautonomic, and immune manifestations. In
short, symptoms other than fatigue must be present for a patient to meet the
criteria. This case definition, which incorporates some of the current research
on dysautonomia, cardiac, and immune problems, was published in the Journal of
Chronic Fatigue Syndrome, Vol. 11 (1) 2003.
It is summarized as follows:
1. POST-EXERTIONAL MALAISE AND FATIGUE: There is a loss of physical and mental
stamina, rapid muscular and cognitive fatigability, post-exertional fatigue,
malaise and/or pain, and a tendency for other symptoms to worsen. A
pathologically slow recovery period (it takes more than 24 hours to recover).
Symptoms exacerbated by stress of any kind. Patient must have a marked degree of
new onset, unexplained, persistent, or recurrent physical and mental fatigue
that substantially reduces activity level.
2. SLEEP DISORDER: Unrefreshing sleep or poor sleep quality; rhythm disturbance.
3. PAIN: Arthralgia and/or myalgia without clinical evidence of inflammatory
responses of joint swelling or redness. Pain can be experienced in the muscles,
joints, or neck and is sometimes migratory in nature. Often, there are
significant headaches of new type, pattern, or severity. [Editor’s note:
neuropathy pain is a common symptom and should be added here as well.]
4. NEUROLOGICAL/COGNITIVE MANIFESTATIONS: Two or more of the following
difficulties should be present: confusion, impairment of concentration and
short-term memory consolidation, difficulty with information processing,
categorizing, and word retrieval, intermittent dyslexia, perceptual/sensory
disturbances, disorientation, and ataxia. There may be overload phenomena:
informational, cognitive, and sensory overload -- e.g., photophobia and
hypersensitivity to noise -- and/or emotional overload which may lead to
relapses and/or anxiety.
5. AT LEAST ONE SYMPTOM OUT OF TWO OF THE FOLLOWING CATEGORIES:
AUTONOMIC MANIFESTATIONS: Orthostatic Intolerance: e.g., neurally mediated
hypotension (NMH), postural orthostatic tachycardia syndrome (POTS), delayed
postural hypotension, vertigo, light-headedness, extreme pallor, intestinal or
bladder disturbances with or without irritable bowel syndrome (IBS) or bladder
dysfunction, palpitations with or without cardiac arrhythmia, vasomotor
instability, and respiratory irregularities.
NEUROENDOCRINE MANIFESTATIONS: loss of thermostatic stability, heat/cold
intolerance, anorexia or abnormal appetite, marked weight change, hypoglycemia,
loss of adaptability and tolerance for stress, worsening of symptoms with stress
and slow recovery, and emotional lability.
IMMUNE MANIFESTATIONS: tender lymph nodes, sore throat, flu-like symptoms,
general malaise, development of new allergies or changes in status of old ones,
and hypersensitivity to medications and/or chemicals.
6. The illness persists for at least 6 months. It usually has an acute onset,
but onset also may be gradual. Preliminary diagnosis may be possible earlier.
The disturbances generally form symptom clusters that are often unique to a
particular patient. The manifestations may fluctuate and change over time.
Symptoms exacerbate with exertion or stress.
This summary is paraphrased from Dr. Kenny van DeMeirleir's book Chronic Fatigue
Syndrome: A Biological Approach, February 2002, CRC Press, pg. 275.
The CDC Bibb county register does rule out:
Bibb County does rule out:
• Pregnancy within past 12 months
• Stroke with no full recovery
• Parkinson’s disease
• Chronic obstructive pulmonary disease (COPD) or congestive heart failure
• Insulin-dependent diabetes
• Uncontrolled diabetes type II (HgbA1c < 9%)
• Anemia
• Uncontrolled hypo- or hyper-thyroidism
• Uncontrolled hypertension (BP > 140/90)
• Sickle cell anemia
• Cancer within 5 years (except basal skin or currentl receiving chemotherapy
• Untreated depression
• Substance abuse problems within the past 2 years
• Anorexia nervosa or bulimia nervosa within the past 5 years
• Schizophrenia, bipolar I or II, or dementia
• Hepatitis B or C
All providers should complete a medical history.
