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The Tomas paper seems to conclude that there is no difference between ME/CFS patients and healthy controls when it comes to mitochondrial complexes. So Tomas et al conclude the mitochondrial dysfunction must be upstream of the mitochondrial respiratory chain:
But these ME/CFS energy metabolism papers often contradict each other. An earlier Tomas paper contradicted the Myhill energy metabolism papers. And the Lawson study found higher than normal ATP levels the cells of ME/CFS patients.