Body versus brain: New evidence for an autoimmune cause of schizophrenia Date: June 6, 2022


Senior Member

Tokyo Medical and Dental University
ummary:Researchers have found that some people with schizophrenia have autoantibodies -- which are made by the immune system and recognize the body's own proteins, rather than outside threats such as viruses or bacteria -- against NCAM1, a protein that's important for communication between brain cells. The patients' autoantibodies also caused schizophrenia-related behaviors in mice. These findings may improve the diagnosis and treatment of a subset of patients with schizophrenia.