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Patent application title: METHOD FOR DETECTION OF XMRV
Inventors: Robert H. Silverman Eric A. Klein Christopher J. Weight Carvell T. Nguyen Jaydip Das Gupta Agents: HAMILTON, BROOK, SMITH & REYNOLDS, P.C. Assignees: Origin: CONCORD, MA US IPC8 Class: AC12Q170FI USPC Class: 435 5 Publication date: 07/22/2010
Patent application number: 20100184015
The present invention relates to the identification of Xenotropic murine leukemia virus (XMRV) nucleic acid by polymerase chain reaction (PCR) analysis (e.g., real time PCR (RT/PCR); nested RT/PCR using Tth DNA polymerase and Hot start polymerase) and the uses thereof. In particular, the invention provides methods for the detection, and in particular early detection, of XMRV in RNA isolated from samples (e.g., urine samples; expressed prostate secretion (EPS)) of prostate cancer patients and normal individuals.