Biopersistence and brain translocation of aluminum adjuvants of vaccines

Gondwanaland

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I am very intrested in aluminum, particularly in its interactions with MAO-A. My serum aluminum is at the top of the local lab range and it was off the chart high in my hair test back in 2013.

Here where I live the soil is particularly rich in aluminum and apparently my body is poorly equipped to deal with it. Also, I have no access to silicon-rich water here. But when I am in a place where I can get it, it is the only water that satiates my thirst ever. Just can't get enough of it.

I have been taking low doses of supplemental silicon and it has been doing wonders for my health. Several external symptoms usually associated with Hashimoto's (dry skin, weak nails) respond well to silicon supplementation.

Coincidentally I took 3 vaccines in 2010 and in 2011 my health went downhill (esp. vascular degeneration). I wonder if aluminum antogonizes silicon in the same way that silicon antagonizes aluminum. Silicon is very important for healthy blood vessels.
 
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Hip

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Silica Removes Aluminum From The Body

As @adreno mentions above, silica (SiO2, silicon dioxide) removes aluminum from the body.

The significant improvements in my ME/CFS that I observed occurring during the two years of 2012 and 2013 may have been the result of me taking up to 120 mg of silica each day during that period.

I took horsetail herb (Equisetum) 800 mg daily in during 2012 and 2013, and horsetail contains 10% to 20% silica.

So it's quite possible that the silica I took was responsible for this improvement of ME/CFS symptoms, via its ability to detoxify aluminum. I had a viral onset of ME/CFS, though, not vaccine-triggered ME/CFS.

Long term treatment with silica might be worth trying for vaccine-triggered ME/CFS: this study found aluminum overload in a case of vaccine-associated ME/CFS and macrophagic myofasciitis in.



(Caveat: in in 2012 / 2013 I also took a four month course of Nexavir, and started taking on a permanent daily basis: selenium, N-acetyl-glucosamine, and very low dose amisulpride. So alternatively one or more these may have been responsible for my ME/CFS improvements)



There is an interesting thread about silica for aluminium detoxification here:

Silicon rich mineral water purges aluminium from body - Supplements - LONGECITY

That thread quotes Prof Christopher Exley, who says the best source of silicon for aluminum detoxification purposes is a silicic acid such as orthosilicic acid (H4SiO4), which according to Exley is much better absorbed than other forms of silicon, including silica from horsetail herb.

The body does not absorb silica directly, but absorbs the small amounts of orthosilicic acid that form when silica is dissolved in water. Orthosilicic acid is formed as this equation indicates: SiO2 + 2 H2O <--> H4SiO4. Silica has a water solubility of 120 mg per liter. 1


There have been suggestions that silicic acids such as orthosilicic acid could be added to the drinking water, to help lower the aluminum burden in the general population.

Orthosilicic acid is found in mineral waters that have a high silicon content. Volvic mineral water has high levels of silicon, 15 mg of silicon per liter (32 mg silica per liter). Fiji mineral water contains 43 mg of silicon per liter (92 mg silica per liter).

Diatomaceous earth is another source of silica, and this contains 80% silica, much more than horsetail.



More info on aluminum and the aluminum hydroxide adjuvant:

• This study found that when 6 doses of aluminum hydroxide (the vaccine adjuvant) were injected into mice, it resulted in significant impairments in a number of motor functions as well as diminished spatial memory.

This study and this study found that the neurotoxicity of aluminum was centered around this metal's effects on the astrocyte cells of the brain. Now interestingly, coxsackievirus B (a virus strongly linked to triggering ME/CFS), has been shown to specifically infect astrocytes as well as the brain's neural progenitor cells (refs: 1, 2, 3). So perhaps if both this virus and high levels of aluminum are present in the brain, this deals a double blow to the astrocyte cells.

• Deferoxamine and malic acid are both chelators of aluminum.



Silica Safety Issues:
I read that silica taken at very high doses, or taken for long periods, has caused irreversible kidney damage:
Silica supplements can product toxicity in people at doses over 100mg per day, but horsetail supplements (which are a natural source of silica) have less toxicity at higher doses than silica, but long-term use or very high doses of horsetail supplements have caused irreversible kidney damage (from excessive silica intake). Women who are pregnant or breastfeeding should not take excessive amounts of silica and neither should people with kidney or heart disease, due to the issues with kidney function. Safety of silica in doses over 50mg has not been established, so it is not advisable to take it higher than this level.

Source: here.
 
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Gondwanaland

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liverock

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I am very interested in aluminum, particularly in its interactions with MAO-A. My serum aluminum is at the top of the local lab range and it was off the chart high in my hair test back in 2013.

Here where I live the soil is particularly rich in aluminum and apparently my body is poorly equipped to deal with it. Also, I have no access to silicon-rich water here. But when I am in a place where I can get it, it is the only water that satiates my thirst ever. Just can't get enough of it.

I have been taking low doses of supplemental silicon and it has been doing wonders for my health. Several external symptoms usually associated with Hashimoto's (dry skin, weak nails) respond well to silicon supplementation.

Coincidentally I took 3 vaccines in 2010 and in 2011 my health went downhill (esp. vascular degeneration). I wonder if aluminum antogonizes silicon in the same way that silicon antagonizes aluminum. Silicon is very important for healthy blood vessels.


Silicon (Si) not only antagonizes Aluminium (Al) but also Lead (Pb) and Mercury (Hg) antagonize Silicon(Si).
Apple pectin is supposed to be good for eliminating Aluminium.



mineral_wheel.gif
 

Gondwanaland

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Silicon (Si) not only antagonizes Aluminium (Al) but also Lead (Pb) and Mercury (Hg) antagonize Silicon(Si).
Apple pectin is supposed to be good for eliminating Aluminium.
I have all of those metals on board.

I can't tolerate malic acid or apple juice, haven't tried apple pectin yet. Silicon supplement has been really helpful.
Malic acid causes me nocturia and consequent insomnia, bruxism, tinnitus, itchy back.
Apple juice causes me a needle-like pain in the bladder.
 

Hip

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All interesting stuff, but I am completely opposed to mass medication via public water supplies.

I agree, but there are other ways of implementing mass medication, in this case perhaps say fortifying soft drinks with orthosilicic acid. Beer already contains silicon (around 19 mg per liter) in the highly bioavailable orthosilicic acid form, and drinking beer can lower aluminum uptake by the body: Role of beer as a possible protective factor in preventing Alzheimer's.

Possibly one advantage of mass medication is that it can bring health benefits to people other than the educated classes who are able to figure out which health supplements to take. Look at the way salt iodization has dramatically reduced the incidence of goiter in regions where the soil is low in iodine.



I was trying to find a map of the US or Europe (but couldn't) showing the natural level of the mineral silicon in the drinking water, and comparing that map to a map of autism prevalence rate (like this autism rate map), or a map of autoimmune disease prevalence. In the US there are vast differences in autism prevalence (more than a factor of 10 difference) from state to state. Assuming that's not down to differences in reporting, these vast differences should be able to provide clues to the etiology — if one could figure out what environmental factor(s) is different between these states.

Might autism / autoimmune diseases / Alzheimer's be lower in areas with naturally high levels of silicon in the drinking water, because of the aluminum detoxifying effects of silicon?
 

Gondwanaland

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Look at the way salt iodization has dramatically reduced the incidence of goiter in regions where the soil is low in iodine.
I read somewhere that it increased incidence of Hashimoto's and I sure can attest for that.
 

Hip

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I read somewhere that it increased incidence of Hashimoto's and I sure can attest for that.

Are you sure that was not for very high doses of iodine, like say the Iodoral supplement which contains 50 mg of iodine per tablet? The amount of iodine you get from your daily salt intake is around one thousandth of that (50 mcg).
 

Gondwanaland

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I got 31 hits when I searched Highwire for 'iodine' and 'Hashimoto' in the title.
Not many of those correlate Hashi's with mass supplementation I suppose.
I couldn't find it among my bookmarks right now, but apparently iodine in table salt isn't absorbable for many people, and they develop Hashimoto's or Graves because they still are iodine deficient in the first place.
Are you sure that was not for very high doses of iodine
I have never supplemented iodine other than in table salt, which I stopped consuming in 2013. Actually a couple of years ago the government issued a new rule reducing table salt iodinization due to too epidemic Hashimoto's in my country.
 

Hip

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@Gondwanaland

Isn't there something of a contradiction in your statements:
(1) Iodine in table salt isn't absorbable for many people, and they develop Hashimoto's or Graves because they still are iodine deficient.

(2) The government issued a new rule reducing table salt iodinization due to too epidemic Hashimoto's in my country.
 

Gondwanaland

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So the government reduced salt iodisation because they thought it increased the risk of, or exacerbated, Hashimoto's?
Exactly. Research showed increased cases of Hashimoto's with salt iodization.

I think what is important here is that a segment of the population will do worse with iodized salt if their selenium intake isn't increased accordingly. It becomes a snowball.

Same thing with aluminum and silica. I see a lot of people around me coping much better with aluminum than my body is capable of. This can be due to genetics, epigenetics and environment.
 

Thomas

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I'm convinced my ME was triggered by the flu vaccine I received 10 days prior to my acute onset. One of my doctor's, Byron Hyde, has seen this all too often in his practice. Not a day goes by that I don't wonder if I could have avoided this hell by just not getting the shot, or would the next virus or whatever I caught trigger it nonetheless....but I guess that's a moot point now.
 
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