BC007 - what are your thoughts?

elvira

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Hello!

With studies for Long Covid and ME/CFS with the drug BC007 starting this summer, I was wondering what people’s thoughts are of the outcome. How much will it help for Long Covid respectively ME/CFS? Is it something to hope for? Please share whatever you’re thinking 🤗

Cheers! (Tagging some people that might know something - @Martin aka paused||M.E. @Pyrrhus @Hip )
 

elvira

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I’m a bit confused since Carmen Scheibenbogen say that 30% of ME-patients have these autoantibodies, while OMF has a swedish study where they found them in 70%. Apparently 90% of Long Covid patients have them. Even if one have them, it’s hard to know how much damage they do and how much of ones symtoms have other causes...
 

vision blue

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Skeptical but curious

So for instance, the anectdote tthat gets solited alot of the 59 year old man says he felt better from long covid symptoms within hours of the first iv treatment. If The drug is supposed to bind auto antibodies, which is I believe what it’s supposed to do, should it make a person feel better that fast? Auto antibodies usually set in motion a slower process involving cytokines (siri transcribed this as Seidel Keynes!) and inflammation and so on and even if you get rid of all the antibodies I would think it would take a while before the effects of the previous damage faded, certainly more than hours But I could be wrong Perhaps also its a different feature of the drug that lead to at least the first wave of feeling better

Do you a citation on the glaucoma and auto antibodies and use of the drug to treat that? I like I might get some more basic info on the rug and mechanisms by looking at that work but I have not found it yet.

In othervwork i do know of finding that SSA autoantibody found on normal pressure glaucoma but thats a different antibody Also dont know what kind of glaucoma the resesrchers first thought thid drug would be good for.

Also havent looked up
Yet how this drug binds to autoantobidies or how the drug increases blood flow

Ive seen one article of theirs in frontiers in ophthalmology but be warned frontiers journals these days are considered predatory journals.

In general, i would t be surprised if alot of viruses affect vasculature.