B6 - sphingolipids, heme, detox, immune function, oh my!

[Learner1]

The whole pyroluria thing needs a lot of fact checking. Unfortunately when you try to do this often there are no facts to be found. See this thread.

I agree with the thread...I'm familiar with Walsh and Pfeiffer and have always been a little skeptical, which is why I suggested fact checking. But always interesting reading....

I just passed it along because of the skin pigmentation paragraph:

In extreme cases low catalase and high H2O2 can lead to de-pigmentation of the skin as in vitiligo. This causes oxidative destruction of melanin and the pigment-producing melanocytes. This is also the mechanism by which high level pyroluria causes early greying of the hair.