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Autism: Infant Neural Sensitivity to Dynamic Eye Gaze - possible pre-MMR predictor?

Firestormm

Senior Member
Messages
5,055
Location
Cornwall England
Infant Neural Sensitivity to Dynamic Eye Gaze Is Associated with Later Emerging Autism

26 January 2012: http://www.cell.com/current-biology/abstract/S0960-9822(11)01469-2


Highlights
Family risk for autism confers subtle differences in brain function in infants
Atypical ERPs in infants when viewing eye gaze data associates with later autism diagnosis
Robust prediction of autism will require an understanding of risk and protective factors

Summary

Autism spectrum disorders (henceforth autism) are diagnosed in around 1% of the population [1]. Familial liability confers risk for a broad spectrum of difficulties including the broader autism phenotype (BAP) [2,3].

There are currently no reliable predictors of autism in infancy, but characteristic behaviors emerge during the second year, enabling diagnosis after this age [4,5]. Because indicators of brain functioning may be sensitive predictors, and atypical eye contact is characteristic of the syndrome [6,7,8,9] and the BAP [10,11], we examined whether neural sensitivity to eye gaze during infancy is associated with later autism outcomes [12,13].

We undertook a prospective longitudinal study of infants with and without familial risk for autism. At 610 months, we recorded infants' event-related potentials (ERPs) in response to viewing faces with eye gaze directed toward versus away from the infant [14].

Longitudinal analyses showed that characteristics of ERP components evoked in response to dynamic eye gaze shifts during infancy were associated with autism diagnosed at 36 months.

ERP responses to eye gaze may help characterize developmental processes that lead to later emerging autism. Findings also elucidate the mechanisms driving the development of the social brain in infancy.

Leftbrainrightbrain on the research: http://leftbrainrightbrain.co.uk/20...aze-is-associated-with-later-emerging-autism/

Leftbrainrightbrain on: Does MMR vaccine travel in time?: http://leftbrainrightbrain.co.uk/2012/01/does-mmr-vaccine-travel-in-time/
 

natasa778

Senior Member
Messages
1,774
The usual rigid-brain-black-and-white-brain verbal diarrhea from the usual suspects over at LBRB. Those guys are Creationists of autism science, feeding themselves on religion of autism being a mysterious god-given gift from heaven (imagine ME/CFS patients calling themselves PHYSIOdiverse and demanding their condition is just a state of being different and should be cherished and not cured)

Here is a brainteaser for you:

- a large proportion of HIV+ children develop autism (of course officially called symptoms of autism lol, but autism being solely a descriptive term for a group of symptoms they are just playing with semantics)
- HIV viral load goes UP UP UP UP following vaccination, especially vaccination with live viruses such as MMR
- the severity of autistic symptoms in HIV+ children correlates to viral load and CD4+ cell function
- live viruses (vaccine strains) have been found alive and well uninhibited by host immune system and having a ball in guts of HIV+ individuals years and decades after vaccine was administered


Go figure.

(loads of references listed here)