heapsreal
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- Messages
- 10,219
- Location
- australia (brisbane)
The round body persister meds seem to me to give the biggest herx reactions.
Does anyone stay on something like doxy all the time for spirochettes but when it comes to round bodies, pulse them in some way to reduce the herx reactions. Im theorizing the round bodies will convert back to spirochettes and get hit with the doxy also.
Recent week of rifampin was a struggle. After a short break i started bactrim, which i usually feel good on, its smashing me too but not as bad as rifampin. I did run 5 days of flagyl and it was ok.
I know flagyl use to be a cyst drug but then research said it wasnt but ive since read it is. Something similar with bactrim also. I think it was Zhang studies a few years after his big 2015 studies mention flagyl and bactrim being round body/cyst/persister drugs. If dapsone hits it then i cant see why bactrim with its similar effects isnt hitting these buggers.
Cheers
Does anyone stay on something like doxy all the time for spirochettes but when it comes to round bodies, pulse them in some way to reduce the herx reactions. Im theorizing the round bodies will convert back to spirochettes and get hit with the doxy also.
Recent week of rifampin was a struggle. After a short break i started bactrim, which i usually feel good on, its smashing me too but not as bad as rifampin. I did run 5 days of flagyl and it was ok.
I know flagyl use to be a cyst drug but then research said it wasnt but ive since read it is. Something similar with bactrim also. I think it was Zhang studies a few years after his big 2015 studies mention flagyl and bactrim being round body/cyst/persister drugs. If dapsone hits it then i cant see why bactrim with its similar effects isnt hitting these buggers.
Cheers