Anxiety/depression related to Coxsackie B viruses, possible interferon connection?

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My mom and I have had serious anxiety/depression from the moment we got sick over 9 years ago now; it was just like someone flipped a switch in our brains. We're infected with Coxsackie B2 and B6 and possibly one or more of the closely related Echoviruses. I'd like to know if Interferon being produced by our cells to fight the viruses is causing that. It seems to make sense since anxiety/depression are common side effects when Interferon is administered medically to Hepatitis and Multiple Sclerosis patients. Anybody know about this?
 
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Hip

Senior Member
Messages
18,305
My mom and I have had serious anxiety/depression from the moment we got sick over 9 years ago now; it was just like someone flipped a switch in our brains. We're infected with Coxsackie B2 and B6 and possibly one or more of the closely related Echoviruses. I'd like to know if Interferon being produced by our cells to fight the viruses is causing that. It seems to make sense since anxiety/depression are common side effects when Interferon is administered medically to Hepatitis and Multiple Sclerosis patients. Anybody know about this?

You might be interested in my account of the generalized anxiety disorder and anhedonia (a symptom of depression) that my coxsackievirus B infection caused me, when I caught it in 2003.

The anxiety I had was moderate to severe, and quite hellish. I finally fixed it with N-acetyl-glucosamine and a few other anti-inflammatory supplements. See here:

Completely eliminated my severe anxiety symptoms with three supplements!

My speculation is that the anxiety arises from the brain inflammation the infection causes. Brain inflammation releases a lot of the neurotransmitter glutamate, which is excitatory, and I think may overactivate areas of the brain like the amygdala, which create anxiety feelings.
 
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