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Antiretrovirals used to treat MS

Rrrr

Senior Member
Messages
1,591
Remember during the XMRV time, when the medical community was saying that it was "irresponsible" to try antiretrovirals for ME/CFS? Well, well, look what we have here! See below. -- Best, rrrr


http://www.healthline.com/health-news/retroviral-drugs-for-hiv-could-treat-ms-040914#text2

Two new studies are under way to test antiretroviral medications on multiple sclerosis (MS) patients. This research is spurred by a narrowly accepted theory that MS may be triggered by human endogenous retroviruses.

In a phase-2 study currently enrolling volunteers, scientists at the Royal London Hospital in England will be following 24 patients who had been given the antiretroviral drug raltegravir, a therapy used to help prevent HIV-positive patients from developing AIDS.

Through a separate study, the Swedish company GeNeuro Innovation has developed a monoclonal antibody called GNbAC1, which targets a protein made by multiple-sclerosis–associated retrovirus (MSRV). GNbAC1 was tested on a small group of 10 patients with two different doses administered intravenously. If approved, it will become the first monoclonal antibody to target a retrovirus in MS. Patients on this drug would receive monthly IV infusions.

... Once [Dr.] Gold started the man on HAART to treat HIV, his MS symptoms disappeared. "Within months of commencing HAART, all MS symptoms gradually improved,” Gold and his colleagues explained in a letter published in the European Journal of Neurology, “Within 2 years, his urinary incontinence was controlled to the extent that he stopped wearing pads and fecal incontinence resolved. He has had no MS relapses."---