It is possible:
Atrial natriuretic peptide is a natural diuretic that is produced in the atrium of the heart.
When you eat soup, your blood volume expanse and your heart is getting larger. This causes the atrial walls to stretch.
It then releases atrial natriuretic peptide, whit’s travels to the bloodstream to the kidney, wit’s then causes the kidney to produce more urine, that will normalize your blood volume and your atrial natriuretic peptide levels again.
In some disease the body is fooled to think there is too much fluid in the body.
These disease are almost all characterized by an increase in endothelin-1, a vasoconstrictor and a potent atrial natriuretic peptide stimulator.
This activation of the endothelin-1/atrial natriuretic peptide pathway results in chronic low blood volume.
The endothelin-1/atrial natriuretic peptide pathway is stimulated by:
Oxidative stress such as isoprostanes and oxidized low-density lipoproteins
Inflammation factors such as interleukin-1, interleukin-3, tumor necrosis factor alpha, interferon gamma, transforming growth factor beta and endotoxin.
Some examples of diseases with increased endotelin-1/atrial natriuretic peptide pathway activation and hypovolemia are: biliary obstruction, sleep apnea, chronic obstructive pulmonary disease with hypoxia and septic shock.
Chronic fatigue syndrome is characterized by low blood volume, cytokines abnormalities, oxidative stress and a low peak oxygen consumption. This low blood volume could be explained by high atrial natriuretic peptide levels stimulated by inflammation, hypoxia or oxidative stress.