I’m looking for a little insight if anyone can help:
About 5-6 months ago my husband had an adverse reaction to a glucocorticosteroid injection(kenalog40). He did not sleep for over two weeks and his body was put under a lot of stress. The original reason he had the steroid injections was that he had bilateral hand weakness which was erroneously diagnosed as tenosynovitis. Since the shot he has developed extreme fatigue, anxiety, brain fog, abnormal neurologic symptoms, insomnia etc and was diagnosed with ME/CFS at the Mayo Clinic. We then met with a Doctor who proposed that it was possible that he had a viral reactivation of EBV or another Herpes virus following iatrogenic immunosuppression from the Steroid. He thinks it’s possible his original hand weakness could have been a virus. His labs showed VCA igg and Nuclear antigen are extremely high.... but it did not show a current active infection on the IgM or Early antigen. It all seems so crazy that he was super human healthy and then pretty much housebound after the shots. He has begun (about 2 weeks ago) to take famvir and his condition has declined... basically his ME symptoms are worse and he’s only taking one tablet a day so far. We are very unsure about this course given that we don’t 100% understand the whole viral theory. The biggest struggle is does he simply have an HPA imbalance from the shot or is it viral? No doctor seems to be able to give a difinitive answer. Has anyone else ever had ME develop following steroid injections? Also what types of symptoms indicate a herx reaction versus just a ME flare? He’s on such a low dose of famvir we weren’t anticipating him to be feeling so bad so soon. ANY insight or related experiences would be so greatly appreciated!
About 5-6 months ago my husband had an adverse reaction to a glucocorticosteroid injection(kenalog40). He did not sleep for over two weeks and his body was put under a lot of stress. The original reason he had the steroid injections was that he had bilateral hand weakness which was erroneously diagnosed as tenosynovitis. Since the shot he has developed extreme fatigue, anxiety, brain fog, abnormal neurologic symptoms, insomnia etc and was diagnosed with ME/CFS at the Mayo Clinic. We then met with a Doctor who proposed that it was possible that he had a viral reactivation of EBV or another Herpes virus following iatrogenic immunosuppression from the Steroid. He thinks it’s possible his original hand weakness could have been a virus. His labs showed VCA igg and Nuclear antigen are extremely high.... but it did not show a current active infection on the IgM or Early antigen. It all seems so crazy that he was super human healthy and then pretty much housebound after the shots. He has begun (about 2 weeks ago) to take famvir and his condition has declined... basically his ME symptoms are worse and he’s only taking one tablet a day so far. We are very unsure about this course given that we don’t 100% understand the whole viral theory. The biggest struggle is does he simply have an HPA imbalance from the shot or is it viral? No doctor seems to be able to give a difinitive answer. Has anyone else ever had ME develop following steroid injections? Also what types of symptoms indicate a herx reaction versus just a ME flare? He’s on such a low dose of famvir we weren’t anticipating him to be feeling so bad so soon. ANY insight or related experiences would be so greatly appreciated!
