Objective ways to study fatigue would be good. This is a new study on fatigue in MS.
(I gave each sentence its own paragraph)http://iopscience.iop.org/0967-3334/33/12/2033
Physiological Measurement Volume 33 Number 12
Fei Yu et al 2012 Physiol. Meas. 33 2033 doi:10.1088/0967-3334/33/12/2033
A wireless body measurement system to study fatigue in multiple sclerosis
Fei Yu1, Arne Bilberg1, Egon Stenager2, Chiara Rabotti3, Bin Zhang1 and Massimo Mischi3
fei@mci.sdu.dk
1 Mads Clausen Institute, University of Southern Denmark, Alsion 2, Sønderborg, DK-6400, Denmark
2 MS-Clinic of Southern Jutland, Department of Neurology, Sønderborg Hospital, Sønderborg, DK-6400, Denmark
3 Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
Fatigue is reported as the most common symptom by patients with multiple sclerosis (MS).
The physiological and functional parameters related to fatigue in MS patients are currently not well established.
A new wearable wireless body measurement system, named Fatigue Monitoring System (FAMOS), was developed to study fatigue in MS.
It can continuously measure electrocardiogram, body-skin temperature, electromyogram and motions of feet.
The goal of this study is to test the ability of distinguishing fatigued MS patients from healthy subjects by the use of FAMOS.
This paper presents the realization of the measurement system including the design of both hardware and dedicated signal processing algorithms.
Twenty-six participants including 17 MS patients with fatigue and 9 sex- and age-matched healthy controls were included in the study for continuous 24 h monitoring.
The preliminary results show significant differences between fatigued MS patients and healthy controls.
In conclusion, the FAMOS enables continuous data acquisition and estimation of multiple physiological and functional parameters.
It provides a new, flexible and objective approach to study fatigue in MS, which can distinguish between fatigued MS patients and healthy controls.
The usability and reliability of the FAMOS should however be further improved and validated through larger clinical trials.