Ambrosia_angel
Senior Member
- Messages
- 544
- Location
- England
Carnitine palmitoyltransferase II deficiency (CPT-II) is a metabolic disorder characterized by an enzymatic defect that prevents long-chain fatty acids from being transported into the mitochondria for utilization as an energy source.
Presentation in adult patients - This exclusively myopathic form is the most prevalent and least severe phenotypic presentation of this disorder. Characteristic symptoms include rhabdomyolysis (breakdown of muscle fibers and subsequent release of myoglobin), myoglobinuria, recurrent myalgia (muscle pain) and weakness. It is important to note that muscle weakness and pain typically resolves within hours to days, and patients appear clinically normal in the intervening periods between attacks. Symptoms are most often exercise-induced, but fasting, a high-fat diet, exposure to cold temperature, or infection (especially febrile illness) can also provoke this metabolic myopathy.
To put it simple most symptoms occur after exercise, so maybe a few hours after and usually a patient recovers after rest. Pain, stiffness (symptoms of fibro) may be an indication there is an undetected problem. Btw weakness isn't always prevalent in this condition but from what I've gathered pain and discomfort is.
Here's the link that alerted me of this condition http://www.fodsupport.org/david.htm
Presentation in adult patients - This exclusively myopathic form is the most prevalent and least severe phenotypic presentation of this disorder. Characteristic symptoms include rhabdomyolysis (breakdown of muscle fibers and subsequent release of myoglobin), myoglobinuria, recurrent myalgia (muscle pain) and weakness. It is important to note that muscle weakness and pain typically resolves within hours to days, and patients appear clinically normal in the intervening periods between attacks. Symptoms are most often exercise-induced, but fasting, a high-fat diet, exposure to cold temperature, or infection (especially febrile illness) can also provoke this metabolic myopathy.
To put it simple most symptoms occur after exercise, so maybe a few hours after and usually a patient recovers after rest. Pain, stiffness (symptoms of fibro) may be an indication there is an undetected problem. Btw weakness isn't always prevalent in this condition but from what I've gathered pain and discomfort is.
Here's the link that alerted me of this condition http://www.fodsupport.org/david.htm