A abnorm severe PEM from 2015

[carmadw]

IT was 2015 and Had an extreme PEM, i could feel how weak my Body was, i couldnt Go - IT was easy to feel, that the weakness in my legs was expanding into Higher parts of the Body, so i refused to walk - IT was very Close with my Meeting with Dr.Bieger from Munic

We tested everything possible- the only Thing WE found was a "Pregnenolone deficit", so i got it AS Supplements
.....after a short time i was able to walk again but IT brought a thought to me - the way the weakness expanded was crazy even for CFS Levels.
I read that apoptosis would have a Effect on the dying cells - a mechanism that causes the neighbour cells to have apoptosis AS well.

I think it could be a quite similar mechanism when IT comes to PEM or AS i See IT - anything with the serotonine Systeme groß wrong, maybe ITS Not the Serotonin itself but more the way the serotonine comes Out of the receptors and then IT meet with cells - the Effect and Feeling of the serotonine are disturbed - WE Just have to See where the serotonine connects and what Changes in the time, definitly Not normal

Do you have any suggestions, associations in your head - please let me read IT

Do you have own theories - Just Partizipation

2015 Dr. Bieger have me cortisone, which worked and Symptoms i Had since two years dissapeard, but i destroyed everything by withdrawal the Lorazepam too fast - i Had extreme pain in my burning head and because of the Low Levels of Pregnenolone, which is very important for the gabba Synthesis, i Had to Take 5 MGs Lorazepam per day, i could swear i Had neurinflammatory MNDA Activity - the lorazepam destroyed the pain caused from IT.

Did anyone of you ever felt a pressure Point in their head- before, maybe they night before a PEM?

The crazy PEM was caused because i slept with 30 mg oxazepam - so i think the PEM has Something to do with gaba Systeme.
To BE fair during the day a doctor came because my Brother didnt leave me alone to Recovery, He called s doctor and she have me the oxazepam - she was later with my Family and explained them my disease, i did almost nothing, but IT caused a new PEM, i felt recovered through the severe PEM ON the day, Just should staying lying ON the Couch.

My thought at night was to destroy the PEM before IT Starts - but that wasnt the Case - IT seemed Like the gaba directly crashed into the Genesis of the PEM - so the gaba Systeme and the antagonistic Systeme are somehow involved in the Nature of PEM

Any thoughts ON that?
Any similar experiences?

 

[Blazer95]

First of all: Jesus your european autocorrect is just as bad as mine i noticed it immidiatly lol.

I have usually an "impending sense of doom" before crashing. I Crash rarely nowdays because i know my illness and If I listen to this feeling and do "aggressive resting" I can usually avoid the worst.

 

[jasperfw]

I read that apoptosis would have a Effect on the dying cells - a mechanism that causes the neighbour cells to have apoptosis AS well.

Interesting. Last year in October I had an extreme crash which gave me many neurological symptoms. Even though my (cognitive) baseline is now higher than before, I still have some neurological (vision) symptoms which haven't improved one inch. Maybe apoptosis is involved in that, as neurons can't regrow?