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I've been busy... but these live things are always a bit of a nightmare. If anything big comes up it will be reported here.
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I got the feeling Vincent new a lot more then he was aloud to say!
and I think dr Bateman was really positive and excited!!
...
5- That XMRV has a very high fidelity rate or that it reproduces each copy of itself exactly. This is unusual in viruses that normally change rapidly in order to stay ahead of the host's immune response. In this case XMRV uses it's perfect copies to attract an attach to other viruses. The attached viruses provide cover for the XMRV and the XMRV provides a key to the cell the other virus needs to get into.
So I think the take home message may be something along these lines. The XMRV is a key to over 80% of the cells in the human body. It reproduces exact copies of itself because it is not a virus that needs to change in order to survive, instead it uses parts of other viruses possibly more than one in order to create a range of quasi species that are able to pass undetected by the host's immune system. Since XMRV has the ability to incorporate more than one type of virus into it's genome it can cause more than one type of cancer and more than one type of disease but it is limited to those viruses that will fit into the deletion sequence that is part of the envelope gene of the XMRV virus.
This would explain why CFS patients have a range of "primary" antibody responses that differ. For instance my antibody response is for EBV which may be what my XMRV is bound to, meaning my body senses that the EBV is their but can't do anything about it no matter how much antibody it throws at it because it is protected by its recombination with XMRV. Someone else may have a "primary" antibody response for HHV-6.
Different recombinations are going to produce slightly different disease patterns, hence the troubling subsets of patients.
I'm Gozer, are you the Key Master? (Too cool, 2 Ghostbusters quotes in 1 day.)
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2. Dr. Bateman talked about the clinical aspects of CFS (bed-side)
She started by stating that when she accepted this webinar invitation several months ago, she was hoping she would be
discussing the latest research done in Utah by Dr. Singh (spelling?). However, publication has been delayed and since
it has not been published yet she cannot say anything. She emphasized though that she was SURE we were going to hear A
LOT from this publication very soon...
She then spent a good part of her talk talking about the good things coming from the XMRV controversy, then was disconnected.
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